Research in Biotechnology at UVA brings together researchers from all biomedical, engineering, and chemical sciences at UVA to promote state-of-the-art collaborative science.  From this innovative science comes conceptual breakthroughs and new products.In 2000, we established a Biotechnology Training Program (BTP) at UVA with the goal of providing fertile ground for the development of future leaders in science and technology.  It is one of only 19 BTPs nationwide.  Our graduates are scientific leaders at major biotechnology companies, federal agencies, and foundations, and lead independent research labs at universities, or are postdoctoral scientists at institutions nationwide.

The BTP offers many enhancements.  The 2 – 3 month company externship training is transformative.  Some students alter career plans towards academia or industrial research.  Others affirm prior career directions or receive unexpected offers of employment.  All make important contributions, some publish articles, and invariably the collaboration enhances thesis projects.  Venues are worldwide, from Boston to San Francisco to Australia, England, Holland, Finland, Germany, Spain and Sweden.

We also offer company tours – including Merck, Pfizer, BD;  panel discussions with industrial leaders – including BTP alumni; as well as seminars and biannual symposia that gather recognized innovators under the umbrella of a broad scientific theme.

Our outstanding mentors from across the sciences at UVA are award-winning leaders in their fields, with success in nurturing the best from our students.  Many hold patents, and several have started companies.  This is an exciting time for our students to be at the frontlines of science and technology.


  • Mazhar Adli
    Identify and target key genomic and epigenomic drivers in cancer
  • Huiwang Ai
    Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
  • Irina Bochkis
    Epigenetic and genetic mechanisms underlying metabolic disease
  • Thomas J. Braciale
    T Lymphocyte Responses To Virus Infection
  • Michael G. Brown
    Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation
  • Steven Caliari
    Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment
  • Linda Columbus
    Biophysical Chemistry: Membrane protein structure, function, and dynamics
  • Douglas W. DeSimone
    Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis
  • Christopher Deppmann
    Elucidating and Understanding the Mechanisms Underlying Nervous System Development
  • Zygmunt S. Derewenda
    Structure-function relationships in proteins
  • Anindya Dutta
    Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer
  • Daniel A. Engel
    Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Influenza, Dengue and Ebola.
  • Victor H. Engelhard
    Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Role of lymphatic endothelial cells in regulating immunity and self-tolerance
  • Sarah E Ewald
    Innate immunity, chronic disease, host-parasite interactions
  • Roseanne M. Ford
    Bacterial attachment and biofilms, microbial transport in porous media
  • Jay W. Fox
    Basement Membrane Structure and Metalloproteinases
  • Andreas Gahlmann
    Super-resolution fluorescence imaging of bacterial cells
  • Barbie Ganser-Pornillos
    The Structural Biology of HIV assembly
  • Alban Gaultier
    Exploring new therapeutics avenues to treat Multiple Sclerosis.
  • Jennifer Guler
    Cell Biology and Parasitology.
  • Young S. Hahn
    Immune regulation for HCV infection and chronic liver inflammation
  • Marie-Louise Hammarskjöld
    Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
  • Tajie H. Harris
    Immune response to infectious disease in the CNS
  • Jeffrey W. Holmes
    Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.
  • Ku-Lung Hsu
    Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry
  • Donald F. Hunt
    Analytical Biochemistry
  • Brant Isakson
    Translating our discoveries in the microcirculation to tangible benefits in patients.
  • Kevin A. Janes
    Systems-biology approaches to cancer biology and virology.
  • Dean H. Kedes
    Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
  • Kimberly Kelly
    Advancement in the design of imaging agents; molecular imaging and radiological sciences.
  • Mark Kester
    Nanotechnologies for targeted drug delivery
  • Jonathan Kipnis
    Neuroimmunology and glia biology in cognition, neurodevelopment and neurodegeneration
  • Bijoy Kundu
    Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy
  • Kyle Lampe
    Neural tissue engineering, biomaterials, drug delivery, redox regulation of stem cell fate, engineering cell-interactive microenvironments
  • James P. Landers
    Bioanalytical Chemistry on Microchips
  • Gordon W. Laurie
    Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense
  • Hui Li
    Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development
  • Xiaowei Lu
    Developmental regulation of planar cell polarity in the mammalian nervous system
  • Kevin R. Lynch
    Chemical biology of sphingosine 1-phosphate
  • Barbara J. Mann
    Pathogenicity of Francisella tularensis and vaccines
  • Michael J McConnell
    The Cause and Consequence of Somatic Mosaicism in Neurons
  • Coleen A. McNamara
    Atherosclerosis, Obesity, Diabetes
  • Christopher A. Moskaluk
    Molecular pathogenesis and genomic analysis of human cancers
  • Kristen Naegle
    Regulation and function of tyrosine phosphorylation in complex networks
  • Jose Oberholzer
    Biotechnology and Biomolecular Engineering (Biomolecular Design, Cellular and Molecular Bioengineering)
  • Jason Papin
    Systems biology, infectious disease, cancer, toxicology, metabolic engineering
  • William R. Pearson
    Protein Evolution; Computational Biology
  • Shayn M. Peirce-Cottler
    Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
  • William A Petri
    Immune mechanisms of defense against enteric (diarrheal) infections
  • Rebecca Pompano
    Bioanalytical tools for inflammatory disease
  • Owen Pornillos
    Structure and assembly of HIV Virus/host interactions; Structural biology of the innate immune system
  • Benjamin W. Purow
    Novel therapeutic approaches to brain cancers and to other neurologic diseases
  • David M. Rekosh
    Human Immunodeficiency; Virus Gene Expression
  • Jeffrey J. Saucerman
    Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
  • Jung-Bum Shin
    Auditory Neurobiology
  • Nathan Swami
    Molecular and bioelectric devices; tissue regeneration.
  • B. Jill Venton
    Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
  • Paul A. Yates
    Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.
  • Mark Yeager
    Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus
  • Chongzhi Zang
    Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Theoretical and computational biophysics
  • J. Julius Zhu
    Neural Circuits in Healthy and Diseased Brains
  • Hui Zong
    Early detection, cancer prevention, and tumor microenvironment
  • Eli Zunder
    Stem Cell Behavior