- Biomedical Sciences Graduate Program | Biophysics
Biophysicists at UVA utilize quantitative approaches to understand the physical and chemical basis of complex biological processes.

Biological processes are studied at every level and across many fields, from the theoretical to the experimental.

The Biophysics Graduate Program at the University of Virginia is one of the oldest in the country. We employ a wide range of experimental and computational approaches in a highly interactive and multidisciplinary environment.  One of our strengths is in the study of membranes, which are of fundamental importance for biological systems. Membranes compartmentalize the cell, thereby controlling the internal cellular environment.  They are sites for energy transduction and signaling.  Finally, many regulatory processes take place at membrane surfaces.

Students in biophysics at UVA gain a strong foundation in biophysical approaches and analysis through innovative research and didactic coursework.

Faculty

  • Huiwang Ai
    Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
  • Stefan Bekiranov
    Physical Modeling of Microarray Hybridization; Analysis of Genomic Tiling Array Data; Bioinformatics; Computational Biology; Regulatory Networks
  • John H. Bushweller
    Structural and Functional Basis for Oncogenesis; Targeted Drug Development; Structural Studies of Membrane Proteins
  • David S. Cafiso
    Molecular Mechanisms for Membrane Transport and Cell Signaling
  • J. David Castle
    Intracellular cholesterol and the regulation of insulin secretion and membrane trafficking.
  • Linda Columbus
    Biophysical Chemistry: Membrane protein structure, function, and dynamics
  • Zygmunt S. Derewenda
    Structure-function relationships in proteins
  • Kateri H. DuBay
    The design of self-assembling nanomaterials
  • Edward H. Egelman
    Structure and Function of Macromolecular Complexes Using Electron Microscopy
  • Roseanne M. Ford
    Bacterial attachment and biofilms, microbial transport in porous media
  • Andreas Gahlmann
    Bacterial cell biology at the molecular level
  • Jennifer Guler
    Cell Biology and Parasitology.
  • Jeffrey W. Holmes
    Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.
  • Ku-Lung Hsu
    Lipid Metabolism in Inflammation and Immunity
  • Donald F. Hunt
    Analytical Biochemistry
  • Brant Isakson
    Intercellular communication as it relates to blood pressure regulation
  • Peter M. Kasson
    Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.
  • Kimberly Kelly
    Advancement in the design of imaging agents; molecular imaging and radiological sciences.
  • Bijoy Kundu
    Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy
  • James P. Landers
    Bioanalytical Chemistry on Microchips
  • Michael B. Lawrence
    Vascular and Molecular Engineering
  • Wladek Minor
    Structure-Function Relationships in Proteins; Structural Genomics; Bioinformatics
  • Cameron Mura
    Structure, function & evolution of RNA-processing assemblies; structural and computational biology; molecular biophysics
  • Robert K. Nakamoto
    Structure-Function of Active Transporters
  • Jason Papin
    Systems biology, infectious disease, cancer, toxicology, metabolic engineering
  • William R. Pearson
    Protein Evolution; Computational Biology
  • Shayn M. Peirce-Cottler
    Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
  • Rebecca Pompano
    Bioanalytical tools for inflammatory disease
  • Owen Pornillos
    Structure and assembly of HIV Virus/host interactions Structural biology of the innate immune system
  • Jeffrey J. Saucerman
    Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
  • Avril V. Somlyo
    Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.
  • Swapnil Sonkusare
    Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension
  • P. Todd Stukenberg
    Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
  • Nathan Swami
    Molecular and bioelectric devices; tissue regeneration.
  • Lukas K. Tamm
    Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
  • B. Jill Venton
    Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
  • Judith M. White
    Virus Entry into Cells: Mechanisms and Development of Anti-Viral Therapeutics
  • Michael C. Wiener
    Structural biology (esp. crystallography) of integral membrane proteins; TonB-dependent active transport across the bacterial outer membrane; cancer-related membrane proteins; crystallization methods development
  • Mark Yeager
    Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus
  • Jochen Zimmer
    Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.