This list, arranged alphabetically, includes all of the BIMS faculty who are approved to train students in at least on of the BIMS degree granting programs. Please feel free to explore this list of over 200 faculty, which highlights the depth and breadth of opportunities available to students who choose to pursue their PhD in our BIMS program.  If your interests are focused in one or a few research disciplines, you may prefer exploring these lists in which our faculty are organized by their research interests.

  • Tarek A. Abbas
    The Ubiquitin System and Human Cancer
  • Roger Abounader
    Basic and translational brain tumor research
  • Paul N. Adler
    Planar signaling, polarity and morphogenesis
  • Mazhar Adli
    Understanding and manipulating the genetics and epigenetics information to study stem cells, differentiation and cancer
  • Herve Agaisse
    Genetic approaches, cellular and molecular biology of intracellular pathogen infection
  • Huiwang Ai
    Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
  • Jayakrishna Ambati
    Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness
  • David T. Auble
    Molecular Mechanisms of Transcriptional Regulation
  • Thomas H. Barker
    My lab is primarily focused on both understanding and manipulating cell-ECM mechanotransduction pathways in homeostasis and disease. Our primary interest is in understanding how cells’ changing microenvironment direct their phenotype and initiate patholo
  • Paula Q. Barrett
    Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.
  • Douglas A. Bayliss
    Mechanisms of neuromodulation in central neurons
  • Mark P. Beenhakker
    Circuit mechanisms of sleep and epilepsy
  • Stefan Bekiranov
    Physical Modeling of Microarray Hybridization; Analysis of Genomic Tiling Array Data; Bioinformatics; Computational Biology; Regulatory Networks
  • Timothy P. Bender
    Regulation of gene expression during lymphocyte development
  • Edward H. Bertram
    Studies of various aspects of epilepsy using anatomy and in vivo and in vitro physiology.
  • Sanchita Bhatnagar
    Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome
  • Michelle Bland
    Molecular mechanisms linking inflammation and insulin signaling to control cell growth and metabolism
  • Robert A. Bloodgood
    Cell-Surface Glycoprotein Dynamics and Cell Locomotion
  • George S. Bloom
    Pathogenic mechanisms in Alzheimer’s Disease and other neurodegenerative disorders
  • Irina Bochkis
    Epigenetic and genetic mechanisms underlying metabolic disease
  • Amy H. Bouton
    Signaling Pathways and Breast Cancer
  • Thomas J. Braciale
    T Lymphocyte Responses To Virus Infection
  • David L. Brautigan
    Protein Phosphorylation in Cell Signaling
  • Michael G. Brown
    NK Cells and Viral Immunity, Genetics of host resistance to viral infection, Immunogenetics, Immune regulation
  • Peter C. Brunjes
    Use the olfactory system to examine general problems in the brain maturation, including the role of afferent activity on tissue development and the interplay between evolution and development.
  • Timothy N. Bullock
    Pathways to enhance T cell function in tumors.
  • John H. Bushweller
    Structural and Functional Basis for Oncogenesis; Targeted Drug Development; Structural Studies of Membrane Proteins
  • David S. Cafiso
    Molecular Mechanisms for Membrane Transport and Cell Signaling
  • Steven Caliari
    Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment
  • Jianhua Cang
  • James E. Casanova
    Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
    Cell Biology of bacterial pathogenesis.
    The innate immune response to bacterial infection.
  • J. David Castle
    Intracellular cholesterol and the regulation of insulin secretion and membrane trafficking.
  • George Christ
    Functional Genomics
  • Mete Civelek
    Systems Genetics Approaches to Understand Cardiometabolic Traits
  • Anna Cliffe
    Herpes Simplex Virus Infection of Neurons
  • James A. Coan
    Neuroscience of Emotional Expression and Individual Emotion-Regulation Capabilities
  • Linda Columbus
    Biophysical Chemistry: Membrane protein structure, function, and dynamics
  • Barry G. Condron
    Regulation and Function Serotonergic Neurons During Development
  • Jessica J. Connelly
    Epigenetic mechanisms involved in complex human disease
  • Jeffrey T. Corwin
    Regeneration and Developmental Biology of the Hearing and Balance Organs in the Vertebrate Ear.
  • Carl E. Creutz
    Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis
  • Alison K. Criss
    Cellular and molecular mechanisms of Neisserial pathogenesis
  • Janet V. Cross
    Contribution of the Inflammatory Microenvironment to Tumor Initiation, Progression and Metastasis; Molecular Mechanisms of Cancer Chemoprevention; Anti-Inflammatory Benefits of Dietary Nutrient Compounds
  • Christopher Deppmann
    Elucidating and Understanding the Mechanisms Underlying Nervous System Development
  • Zygmunt S. Derewenda
    Structure-function relationships in proteins
  • Isabelle Derre
    Host/pathogen Interaction – Chlamydia Infection
  • Bimal N. Desai
    Ion channels and Ca2+-signaling in inflammation and immunity
  • Douglas W. DeSimone
    Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis
  • Thomas Jason Druzgal
    Multi-modal brain MRI to study different aspects of neurodegenerative diseases. Effects of mild traumatic brain injury on student athletes. Parkinson’s Disease and essential tremor.
  • Kateri H. DuBay
    The design of self-assembling nanomaterials
  • Andrew Dudley
    Tumor microenvironment and mechanisms of tumor neovascularization
  • Anindya Dutta
    Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer
  • Noelle Dwyer
    Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance
  • Edward H. Egelman
    Structure and Function of Macromolecular Complexes Using Electron Microscopy
  • Daniel A. Engel
    Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Influenza, Dengue and Ebola.
  • Victor H. Engelhard
    Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Role of lymphatic endothelial cells in regulating immunity and self-tolerance
  • Loren D. Erickson
    Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders
  • Alev Erisir
    Developmental Plasticity and Neuropathology of Synaptic Circuitries.
  • Sarah E Ewald
    Innate immunity, chronic disease, host-parasite interactions
  • Charles R. Farber
    Systems Genetics of Skeletal Development and Maintenance
  • Robin A. Felder
    Clinical Chemistry and Toxicology. Medical Automation Research. Neurotransmitters, cell surface receptors and intracellular second messengers.
  • Heather Ferris
    The Role of Diabetes in Cognitive Decline
  • Roseanne M. Ford
    Bacterial attachment and biofilms, microbial transport in porous media
  • Jay W. Fox
    Basement Membrane Structure and Metalloproteinases
  • Brent A. French
    Novel Therapies for Treating and Preventing Ischemic Heart Disease
  • Andreas Gahlmann
    Bacterial cell biology at the molecular level
  • Francine Garrett-Bakelman
    Acute Myeloid Leukemia: molecular and cellular biology events which mediate aberrant epigenetic and transcriptional mechanisms during disease establishment and progression
  • Felicia Gaskin
    Alzheimer’s disease, autoimmune disease, cytoskeletal proteins, microtubule assembly
  • Alban Gaultier
    Exploring new therapeutics avenues to cure Multiple Sclerosis.
  • Bradley Gelfand
    Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.
  • Daniel Gioeli
    Signal transduction in cancer cells
  • Adam N. Goldfarb
    Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
  • Howard P. Goodkin
    Status epilepticus
  • Robert M. Grainger
    Molecular embryology–gene regulation in cells committed to specific developmental lineages
  • Patrick A. Grant
    Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer
  • Tobias Grossmann
    Brain processes that underpin social interaction and cognition during infancy
  • Michael J. Guertin
    Transcription, Chromatin, Cancer, Molecular Biology, Genomics, and Computational Biology
  • Ali D. Guler
    Behavior and epigenetics; Building and wiring the brain; Neurodevelopmental and neuropsychiatric disorders; Biological timing: circadian rhythms.
  • Jennifer Guler
    Cell Biology and Parasitology.
  • Patrice G. Guyenet
    Neural control of blood pressure and respiration
  • John T. Hackett
    Synaptic Transmission
  • Young S. Hahn
    Immune regulation for HCV infection and chronic liver inflammation
  • Adrian J. Halme
    Regeneration and Systemic Responses to Tissue Damage
  • Marie-Louise Hammarskjöld
    Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
  • Tajie H. Harris
    Immune response to infectious disease in the CNS
  • Thurl E Harris
    Molecular mechanisms controlling insulin signaling and fat synthesis.
  • Erik L. Hewlett
    Structure and Function of Bacterial Toxins: Roles in Microbial Pathogenesis and Uses in Biomedical Research
  • David Hill
    Development and plasticity of sensory systems
  • Barry T. Hinton
    Morphogenesis of the Developing Wolffian/Epididymal duct
  • Jay Hirsh
    Molecular genetics; development and function of neurotransmitter-synthesizing neurons in Drosophila
  • Joel W. Hockensmith
    Novel antiprotozoan and anticancer compounds from antibiotic-resistant bacteria
  • Jeffrey W. Holmes
    Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.
  • Ku-Lung Hsu
    Lipid Metabolism in Inflammation and Immunity
  • Song Hu
    Photoacoustic imaging, light microscopy, neuroscience, microvascular biology
  • Molly A. Hughes
    Biodefense and emerging pathogens
  • Donald F. Hunt
    Analytical Biochemistry
  • Brant Isakson
    Intercellular communication as it relates to blood pressure regulation
  • Kevin A. Janes
    Systems-biology approaches to cancer biology and virology.
  • Laura Jansen
    Pediatric Epilepsy, Human Brain Development, Inhibitory Neurotransmission
  • Alexandra Kadl
    Lung injury and repair, sepsis
  • Jaideep Kapur
    Pathophysiology of Status Epilepticus; Plasticity of GABAergic Synaptic Transmission
  • David F Kashatus
    The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
  • Peter M. Kasson
    Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.
  • Masashi Kawasaki
    Neuroethology of electric fish
  • Dean H. Kedes
    Human Herpes virus associated with malignancy, including Kaposi’s Sarcoma
  • Raymond E. Keller
    Cellular and molecular mechanisms of morphogenesis
  • Kimberly Kelly
    Advancement in the design of imaging agents; molecular imaging and radiological sciences.
  • Melissa M. Kendall
    Mechanisms used by Bacterial Pathogens to Integrate Host- and Bacterial-derived Signals to Sense their Environment, Coordinate Gene Expression, and Cause Disease
  • Mark Kester
    Nanotechnologies for targeted drug delivery
  • Gilbert Kinsey
    Acute Kidney Injury, Regulatory T Cells, Innate Immune Response
  • Jonathan Kipnis
    Neuroimmunology and glia biology in cognition, neurodevelopment and neurodegeneration
  • Keith G. Kozminski
    Regulation of Polarized Morphogenesis
  • Christopher M. Kramer
    Cardiac magnetic resonance imaging, myocardial disease, atherosclerotic plaque imaging, peripheral arterial disease
  • Sarah C Kucenas
    The role of glia in the development, maintenance and regeneration of the nervous system
  • Bijoy Kundu
    Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy
  • Kyle Lampe
    Neural tissue engineering, biomaterials, drug delivery, redox regulation of stem cell fate, engineering cell-interactive microenvironments
  • Charles Landen
    Mechanisms of Chemotherapy Resistance in Ovarian and Other Gynecologic Malignancies
  • James P. Landers
    Bioanalytical Chemistry on Microchips
  • Victor E. Laubach
    Translational research into understanding cell and molecular mechanisms of lung ischemia-reperfusion (IR) injury following transplantation and defining new therapeutic targets to prevent such injury.
  • Gordon W. Laurie
    Role of Prosecretory Mitogen ‘Lacritin’ in Epithelial Homeostasis, Secretion and Innate Defense
  • Michael B. Lawrence
    Vascular and Molecular Engineering
  • John S. Lazo
    The mechanism of action of small molecules and the fundamental biological role of protein tyrosine phosphatases
  • Kevin S. Lee
    Neuronal Vulnerability: A Study of Cellular Mechanism
  • Norbert Leitinger
    Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
  • Hui Li
    Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development
  • Xiaorong Liu
    Developing novel neuroprotection strategies to preserve vision in glaucoma
  • Ulrike M Lorenz
    Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
  • Thomas P Loughran, Jr.
    Hematologic malignancies; bone marrow disorders; leukemia; large granular lymphocyte (LGL)
  • Xiaowei Lu
    Developmental regulation of planar cell polarity in the mammalian nervous system
  • Chance John Luckey
    Immune Memory
  • John R. Lukens
    Neuroinflammatory disease
  • Kevin R. Lynch
    Chemical biology of sphingosine 1-phosphate
  • Wendy J. Lynch
    Behavioral Pharmacology, Sex Differences, Animal Models of Addiction
  • Mani S. Mahadevan
    Molecular Mechanisms of Myotonic Muscular Dystrophy
  • James W. Mandell
    Identification of Novel Biomarkers for Inflammatory Myopathies
  • Barbara J. Mann
    Pathogenicity of Francisella tularensis and vaccines
  • Carol A. Manning
    Dementia neurodegenerative disease & cognition
  • Marty W. Mayo
    Transcriptional Regulation by NFKB
  • Michael J McConnell
    The Cause and Consequence of Somatic Mosaicism in Neurons
  • Coleen A. McNamara
    Atherosclerosis, Obesity, Diabetes
  • C. Daniel Meliza
    Neural Mechanisms of Pattern Learning and Recognition in the Auditory System
  • Deforest Mellon
    Sensory System Organization and Development
  • Clint Miller
    Genetic variation, Complex diseases, Coronary artery disease, Regulatory mechanisms, Vascular biology and physiology
  • Wladek Minor
    Structure-Function Relationships in Proteins; Structural Genomics; Bioinformatics
  • Golam Mohi
    Cell signaling, hematopoietic stem cell biology, molecular and epigenetic mechanisms of leukemia.
  • James P. Morris
    Social perception and cognition; Social Neuroscience; Human Neuroscience
  • Christopher A. Moskaluk
    Molecular pathogenesis and genomic analysis of human cancers
  • Cameron Mura
    Structure, function & evolution of RNA-processing assemblies; structural and computational biology; molecular biophysics
  • Robert K. Nakamoto
    Structure-Function of Active Transporters
  • James P. Nataro
    Pathogenesis of diarrheagenic Escherichia coli and Shigella.
  • Eyleen Jorgelina O’Rourke
    Obesity and Aging
  • Gary K. Owens
    Epigenetic Control of Perivascular and Stem Cell Plasticity/Trans-Differentiation during Injury-Repair and in Disease
  • Jason Papin
    Systems biology, infectious disease, cancer, toxicology, metabolic engineering
  • David Parichy
    Long-distance communication by specialized cellular projections, intersections of hormonal controls with local mechanisms of differentiation and morphogenesis, establishment and recruitment of post-embryonic stem cells during development and regeneration,
  • Kwon-Sik Park
    Mechanisms of tumor progression and homeostasis
  • Bryce M. Paschal
    Nuclear Transport, Signaling, and Cancer
  • Manoj Patel
    Modulation of sodium channel gating by beta subunits and novel sodium channel blockers; Synaptic transmission in dorsal horn neurons
  • William R. Pearson
    Protein Evolution; Computational Biology
  • Shayn M. Peirce-Cottler
    Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
  • Lucy F. Pemberton
    Nuclear Transport in Chromatin Assembly and Transcriptional Regulation
  • Edward Perez-Reyes
    Exploring epilepsy circuits then preventing seizures using AAV-based gene therapies.
  • William A Petri
    Molecular mechanisms of pathogenesis of parasitic infection
  • K. Kevin Pfister
    Regulation of Cytoplasmic Dynein for Membrane Bounded Organelle Trafficking in Axons
  • Rebecca Pompano
    Our lab develops methods based on microfluidic culture systems, bioanalytical techniques, and spatially resolved simulations to quantify the spatiotemporal dynamics of the inflammatory cascade and develop targeted therapies.
  • Owen Pornillos
    Structure and assembly of HIV Virus/host interactions Structural biology of the innate immune system
  • Dennis R. Proffitt
    Human Perception & Cognition
  • Ignacio Provencio
    The Role of Melanopsin Retinal Ganglion Cells in the Photic Regulation of Mammalian Circadian Rhythms
  • Javier Provencio
    Innate Inflammatory Pathways Associated with Acute Aneurysmal Subarachnoid Hemorrhage
  • Benjamin W. Purow
    Novel therapeutic approaches to brain cancers and to other neurologic diseases
  • Girija Ramakrishnan
    Iron-uptake mechanisms and Virulence Factors of Francisella tularensis; Microbial Pathogenesis
  • Aakrosh Ratan
    Genomics, Molecular Evolution, Algorithm Design and Analysis
  • Kodi S. Ravichandran
    Apoptotic cell clearance mechanisms in health and disease
  • Stefanie Redemann
    Spindle assembly, the structure function relation and the basics of the huge variability of spindle size, architecture and mechanics between different tissues as well as different species
  • David M. Rekosh
    Human Immunodeficiency; Virus Gene Expression
  • Stephen S. Rich
    Genetic basis of common human disease, including type 1 diabetes, diabetic complications, ischemic stroke, atherosclerosis
  • Melanie Rutkowski
    Influence of commensal microbes on immune homeostasis, anti-tumor immunity, and metastasis
  • Michele Sale
    Genetics of complex disease
  • Jeffrey J. Saucerman
    Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
  • Dorothy A. Schafer
    Mechanisms of actin assembly during cell migration and membrane traffic
  • Ira G. Schulman
    Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism, atherosclerosis, Small molecule approaches to drug discovery
  • Michael M. Scott
    Investigation of the neuronal circuits and epigenetic modifications involved in the control of food and drug reward
  • Nathan Sheffield
    computational biology & bioinformatics; high performance computing; epigenomics & chromatin; pediatric cancer; computational regulatory genomics; machine learning
  • Weibin Shi
    Cellular and genetic determinants of atherosclerosis and restenosis.
  • Jung-Bum Shin
    Auditory Neurobiology
  • Margaret A. Shupnik
    Hypothalamic Peptide and Steroid Regulation of Pituitary Gene Transcription; Estrogen Action in Neuroendocrine and Reproductive Tissues; Estrogen Action in Breast Cancer
  • Sarah Siegrist
    Regulation of neural stem cell proliferation by extracellular factors, local and systemic. Intrinsic signaling programs regulating neural stem cell fate decisions: death versus survival. Functional and molecular similarities between Drosophila and mammal
  • Jogender Tushir Singh
    Tailored fit targeting approaches: Cancer Immunotherapy, Bispecific Antibodies, Antibody-siRNA conjugates, Application in Cancer therapeutics
  • Jeffrey S. Smith
    Transcriptional Silencing and Aging in Yeast
  • M. Mitchell Smith
    Functional Genomics of Histones, Chromatin, and Protein Acetylation Signaling in Cancer and the Cell Cycle
  • Nina J. Solenski
    Mechanisms of cerebral ischemia
  • Avril V. Somlyo
    Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.
  • Swapnil Sonkusare
    Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension
  • James Radford Stone
    Traumatic Brain Injury
  • P. Todd Stukenberg
    Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
  • Ann E. Sutherland
    Cell Matrix Interactions In Mouse Development
  • Nathan Swami
    Molecular and bioelectric devices; tissue regeneration.
  • Lukas K. Tamm
    Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
  • Bernard V. Thisse
    Molecular control of embryonic development
  • Christine I. Thisse
    Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine
  • Kenneth S. Tung
    Mechanisms of Tolerance and Autoimmunity to Gonad-Specific Antigens
  • Scott B. Vande Pol
    We study papillomavirus oncoproteins as probes to elucidate cellular pathways regulating cellular signal transduction, and the development of cancer. Projects: Oncoprotein E6 and the regulation of integrin signaling and Cdc48.
  • B. Jill Venton
    Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
  • Yuh-Hwa Wang
    Genome instability in human disease
  • Judith M. White
    Virus Entry into Cells: Mechanisms and Development of Anti-Viral Therapeutics
  • Michael C. Wiener
    Structural biology (esp. crystallography) of integral membrane proteins; TonB-dependent active transport across the bacterial outer membrane; cancer-related membrane proteins; crystallization methods development
  • Cedric L. Williams
    Studies of various aspects of learning, memory, olfactory discrimination and explosive detection. We develop computer driven learning programs that produce optimal olfactory discrimination and detection learning in rodents.
  • Bettina Winckler
    Endosomal function and dysfunction in neurons
  • Matthew J Wolf
    Identification of genes and pathways that cause or modify cardiac hypertrophy and heart failure.
  • Judith A. Woodfolk
    Cellular and molecular mechanisms of allergic disease in humans.
  • David Wotton
    Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling
  • Zhen Yan
    Molecular and Signaling Mechanisms of Skeletal Muscle Plasticity
  • Paul A. Yates
    Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.
  • Mark Yeager
    Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus
  • Jing Yu
    Mammalian kidney development
  • Chongzhi Zang
    Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Theoretical and computational biophysics
  • Steven L. Zeichner
    Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.
  • Scott O. Zeitlin
    Mechanisms of Huntington’s Disease Pathogenesis
  • J. Julius Zhu
    Neural Circuits in Healthy and Diseased Brains
  • Jochen Zimmer
    Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.
  • Hui Zong
    Mouse models of brain cancers
  • Eli Zunder
    Stem Cell Behavior
  • Zhiyi Zuo
    Neuroscience and Anesthetic Neuroprotection