The Microbiology, Immunology, and Cancer Biology (MIC) Department is home to the PhD degree-granting program in Microbiology.  PhD students study under internationally-recognized scientists in the areas of immunology, cancer biology, virology, bacteriology, infectious diseases, biodefense, cell-signaling, and gene regulation. The wide variety of choices in laboratories and coursework coupled with flexible departmental requirements enables each student to design a custom-tailored training program.

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Program Faculty

  • Roger Abounader
    Basic and translational brain tumor research
  • Herve Agaisse
    Genetic approaches, cellular and molecular biology of intracellular pathogen infection
  • Timothy P. Bender
    Regulation of gene expression during lymphocyte development
  • Amy H. Bouton
    Signaling Pathways and Breast Cancer
  • Thomas J. Braciale
    T Lymphocyte Responses To Virus Infection
  • David L. Brautigan
    Protein Phosphorylation in Cell Signaling
  • Jay C. Brown
    Structure and Assembly of the Herpes Simplex Virus Capsid.
  • Michael G. Brown
    NK Cells and Viral Immunity, Genetics of host resistance to viral infection, Immunogenetics, Immune regulation
  • Timothy N. Bullock
    Pathways to enhance T cell function in tumors.
  • James E. Casanova
    Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
    Cell Biology of bacterial pathogenesis.
    The innate immune response to bacterial infection.
  • Anna Cliffe
    Herpes Simplex Virus Infection of Neurons
  • Alison K. Criss
    Cellular and molecular mechanisms of Neisserial pathogenesis
  • Isabelle Derre
    Host/pathogen Interaction – Chlamydia Infection
  • Bimal N. Desai
    Ion channels and Ca2+-signaling in inflammation and immunity
  • Andrew Dudley
    Tumor microenvironment and mechanisms of tumor neovascularization
  • Daniel A. Engel
    Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Influenza, Dengue and Ebola.
  • Victor H. Engelhard
    Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Role of lymphatic endothelial cells in regulating immunity and self-tolerance
  • Loren D. Erickson
    Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders
  • Sarah E Ewald
    Innate immunity, chronic disease, host-parasite interactions
  • Jay W. Fox
    Basement Membrane Structure and Metalloproteinases
  • Daniel Gioeli
    Signal transduction in cancer cells
  • Jennifer Guler
    Cell Biology and Parasitology
  • Young S. Hahn
    Immune regulation for HCV infection and chronic liver inflammation
  • Marie-Louise Hammarskj√∂ld
    Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
  • Tajie H. Harris
    Immune response to infectious disease in the CNS
  • Erik L. Hewlett
    Structure and Function of Bacterial Toxins: Roles in Microbial Pathogenesis and Uses in Biomedical Research
  • Molly A. Hughes
    Biodefense and emerging pathogens
  • David F Kashatus
    The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
  • Dean H. Kedes
    Human Herpes virus associated with malignancy, including Kaposi’s Sarcoma
  • Melissa M. Kendall
    Mechanisms used by Bacterial Pathogens to Integrate Host- and Bacterial-derived Signals to Sense their Environment, Coordinate Gene Expression, and Cause Disease
  • Ulrike M Lorenz
    Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
  • Thomas P Loughran, Jr.
    Hematologic malignancies; bone marrow disorders; leukemia; large granular lymphocyte (LGL)
  • Barbara J. Mann
    Pathogenicity of Francisella tularensis and vaccines
  • Coleen A. McNamara
    Atherosclerosis, Obesity, Diabetes
  • James P. Nataro
    Pathogenesis of diarrheagenic Escherichia coli and Shigella.
  • Kwon-Sik Park
    Mechanisms of tumor progression and homeostasis
  • Lucy F. Pemberton
    Nuclear Transport in Chromatin Assembly and Transcriptional Regulation
  • William A Petri
    Molecular mechanisms of pathogenesis of parasitic infection
  • Rebecca Pompano
    Our lab develops methods based on microfluidic culture systems, bioanalytical techniques, and spatially resolved simulations to quantify the spatiotemporal dynamics of the inflammatory cascade and develop targeted therapies.
  • Girija Ramakrishnan
    Iron-uptake mechanisms and Virulence Factors of Francisella tularensis; Microbial Pathogenesis
  • Kodi S. Ravichandran
    Apoptotic cell clearance mechanisms in health and disease
  • David M. Rekosh
    Human Immunodeficiency; Virus Gene Expression
  • Melanie Rutkowski
    Influence of commensal microbes on immune homeostasis, anti-tumor immunity, and metastasis
  • M. Mitchell Smith
    Functional Genomics of Histones, Chromatin, and Protein Acetylation Signaling in Cancer and the Cell Cycle
  • Kenneth S. Tung
    Mechanisms of Tolerance and Autoimmunity to Gonad-Specific Antigens
  • Judith M. White
    Virus Entry into Cells: Mechanisms and Development of Anti-Viral Therapeutics
  • Judith A. Woodfolk
    Cellular and molecular mechanisms of allergic disease in humans.
  • Steven L. Zeichner
    Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.
  • Hui Zong
    Mouse models of brain cancers