Robert M. Grainger


  • AB, Stanford University
  • PhD, University of California, Berkeley
  • Postdoc, Yale University

Primary Appointment

  • Professor, Biology


Research Interest(s)

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Research Description

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Selected Publications

  • Nakayama T, Fisher M, Nakajima K, Odeleye A, Zimmerman K, Fish M, Yaoita Y, Chojnowski J, Lauderdale J, Netland P, Grainger R. Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients. Developmental biology. 2015. PMID: 25724657
  • Fish M, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple D, Grainger R. Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character. Developmental biology. 2014. PMID: 25224223
  • Nakayama T, Blitz I, Fish M, Odeleye A, Manohar S, Cho K, Grainger R. Cas9-based genome editing in Xenopus tropicalis. Methods in enzymology. 2014;546 355-75. PMID: 25398349 | PMCID: PMC4284096
  • Xenopus tropicalis as a Model Organism for Genetics and Genomics: Past, Present, and Future. Methods in molecular biology (Clifton, N.J.). 2012;917 3-15. PMID: 22956079 | PMCID: PMC3918953
  • Jin H, Fisher M, Grainger R. Defining progressive stages in the commitment process leading to embryonic lens formation. Genesis (New York, N.Y. : 2000). 2012;50(10): 728-40. PMID: 22566346 | PMCID: PMC3870160
  • Wei S, Xu G, Bridges L, Williams P, Nakayama T, Shah A, Grainger R, White J, DeSimone D. Roles of ADAM13-regulated Wnt activity in early Xenopus eye development. Developmental biology. 2012;363(1): 147-54. PMID: 22227340 | PMCID: PMC3288294
  • Fish M, Nakayama T, Grainger R. Simple, fast, tissue-specific bacterial artificial chromosome transgenesis in Xenopus. Genesis (New York, N.Y. : 2000). 2011;50(3): 307-15. PMID: 22084035 | PMCID: NIHMS343469
  • Hellsten U, Harland R, Gilchrist M, Hendrix D, Jurka J, Kapitonov V, Ovcharenko I, Putnam N, Shu S, Taher L, Blitz I, Blumberg B, Dichmann D, Dubchak I, Amaya E, Detter J, Fletcher R, Gerhard D, Goodstein D, Graves T, Grigoriev I, Grimwood J, Kawashima T, Lindquist E, Lucas S, Mead P, Mitros T, Ogino H, Ohta Y, Poliakov A, Pollet N, Robert J, Salamov A, Sater A, Schmutz J, Terry A, Vize P, Warren W, Wells D, Wills A, Wilson R, Zimmerman L, Zorn A, Grainger R, Grammer T, Khokha M, Richardson P, Rokhsar D. The genome of the Western clawed frog Xenopus tropicalis. Science (New York, N.Y.). 2010;328(5978): 633-6. PMID: 20431018 | PMCID: PMC2994648
  • Ogino H, Fisher M, Grainger R. Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification. Development (Cambridge, England). 2007;135(2): 249-58. PMID: 18057103 | PMCID: PMC3918164
  • Ogino H, McConnell W, Grainger R. High-throughput transgenesis in Xenopus using I-SceI meganuclease. Nature protocols. 2007;1(4): 1703-10. PMID: 17487153
  • Ogino H, McConnell W, Grainger R. Highly efficient transgenesis in Xenopus tropicalis using I-SceI meganuclease. Mechanisms of development. 2006;123(2): 103-13. PMID: 16413175