Norbert Leitinger


  • PhD, University of Vienna

Primary Appointment

  • Associate Professor, Pharmacology


Research Interest(s)

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Research Description

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Selected Publications

  • Adamson S, Leitinger N. The role of pannexin1 in the induction and resolution of inflammation. FEBS letters. 2014;588(8): 1416-22. PMID: 24642372 | PMCID: PMC4060616
  • Leitinger N, Schulman I. Phenotypic polarization of macrophages in atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology. 2013;33(6): 1120-6. PMID: 23640492 | PMCID: PMC3745999
  • Halterman J, Kwon H, Leitinger N, Wamhoff B. NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration. Frontiers in physiology. 2012;3 313. PMID: 22934063 | PMCID: PMC3429083
  • Lohman A, Weaver J, Billaud M, Sandilos J, Griffiths R, Straub A, Penuela S, Leitinger N, Laird D, Bayliss D, Isakson B. S-nitrosylation inhibits pannexin 1 channel function. The Journal of biological chemistry. 2012;287(47): 39602-12. PMID: 23033481 | PMCID: PMC3501028
  • Meher A, Sharma P, Lira V, Yamamoto M, Kensler T, Yan Z, Leitinger N. Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance. Free radical biology & medicine. 2012;52(9): 1708-15. PMID: 22370093 | PMCID: PMC3383807
  • Adamson S, Leitinger N. Phenotypic modulation of macrophages in response to plaque lipids. Current opinion in lipidology. 2011;22(5): 335-42. PMID: 21841486 | PMCID: PMC3979355
  • Kadl A, Sharma P, Chen W, Agrawal R, Meher A, Rudraiah S, Grubbs N, Sharma R, Leitinger N. Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2. Free radical biology & medicine. 2011;51(10): 1903-9. PMID: 21925592 | PMCID: PMC3197756
  • Manichaikul A, Wang Q, Shi Y, Zhang Z, Leitinger N, Shi W. Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression. American journal of physiology. Heart and circulatory physiology. 2011;301(3): H1056-61. PMID: 21666121 | PMCID: PMC3191074
  • Rao J, DiGiandomenico A, Artamonov M, Leitinger N, Amin A, Goldberg J. Host derived inflammatory phospholipids regulate rahU (PA0122) gene, protein, and biofilm formation in Pseudomonas aeruginosa. Cellular immunology. 2011;270(2): 95-102. PMID: 21679933 | PMCID: PMC3415270
  • Rao J, Elliott M, Leitinger N, Jensen R, Goldberg J, Amin A. RahU: an inducible and functionally pleiotropic protein in Pseudomonas aeruginosa modulates innate immunity and inflammation in host cells. Cellular immunology. 2011;270(2): 103-13. PMID: 21704311 | PMCID: PMC3432393
  • Heberlein K, Straub A, Best A, Greyson M, Looft-Wilson R, Sharma P, Meher A, Leitinger N, Isakson B. Plasminogen activator inhibitor-1 regulates myoendothelial junction formation. Circulation research. 2010;106(6): 1092-102. PMID: 20133900 | PMCID: PMC2848897
  • Sharma R, Sharma P, Kim Y, Leitinger N, Lee J, Fu S, Ju S. IL-2-controlled expression of multiple T cell trafficking genes and Th2 cytokines in the regulatory T cell-deficient scurfy mice: implication to multiorgan inflammation and control of skin and lung inflammation. Journal of immunology (Baltimore, Md. : 1950). 2010;186(2): 1268-78. PMID: 21169543 | PMCID: PMC3136806
  • "Obese" smooth muscle cells fail to assemble collagen fibrils. Circulation research. 2009;104(7): 826-8. PMID: 19359604
  • Cherepanova O, Pidkovka N, Sarmento O, Yoshida T, Gan Q, Adiguzel E, Bendeck M, Berliner J, Leitinger N, Owens G. Oxidized phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration. Circulation research. 2009;104(5): 609-18. PMID: 19168440 | PMCID: PMC2758767
  • Johnstone S, Ross J, Rizzo M, Straub A, Lampe P, Leitinger N, Isakson B. Oxidized phospholipid species promote in vivo differential cx43 phosphorylation and vascular smooth muscle cell proliferation. The American journal of pathology. 2009;175(2): 916-24. PMID: 19608875 | PMCID: PMC2716985
  • Kadl A, Galkina E, Leitinger N. Induction of CCR2-dependent macrophage accumulation by oxidized phospholipids in the air-pouch model of inflammation. Arthritis and rheumatism. 2009;60(5): 1362-71. PMID: 19404946 | PMCID: PMC2745196
  • Wright M, Kim J, Hock T, Leitinger N, Freeman B, Agarwal A. Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions. The Biochemical journal. 2009;422(2): 353-61. PMID: 19534727 | PMCID: PMC2881470