Michele Sale

Education

  • PhD, University of Tasmania
  • BS, University of Tasmania

Primary Appointment

  • Associate Professor, Public Health Sciences

Contact

Research Interest(s)

Genetics of complex disease

Research Description

My group's research is aimed at identifying and characterizing genetic contributors to complex disease susceptibility. We are using a genome-wide association study (GWAS) approach to: (1) identify and characterize genetic variants that contribute to type 2 diabetes susceptibility in African American Sea Islanders of coastal South Carolina and Georgia, and (2) identify variants contributing to lipoprotein subclasses - predictors of cardiovascular outcomes - measured using nuclear magnetic resonance (NMR). [NIH Grant DK084350] About 25 percent of people who recover from their first stroke will have another stroke within 5 years. The Vitamin Intervention for Stroke Prevention (VISP) trial enrolled ischemic stroke patients, randomized them to either high or low dose folic acid, vitamin B6 and vitamin B12, then documented incident vascular events over 2 years.  Our studies aim to (1) identify genetic variants associated with recurrent ischemic stroke and combined vascular endpoints; (2) gain insights into individual responses to B vitamin therapy; (3) develop predictive models of recurrent stroke, incorporating genetic and clinical information. This study is part of GARNET, the Genomics and Randomized Trials Network. [NIH Grant HG005160] Otitis media is an inflammation of the middle ear caused by infection. Family studies have demonstrated a role for genetic factors in disease susceptibility. Projects underway aim to (1) identify susceptibility variants for chronic and recurrent otitis media using both GWAS and linkage approaches, (2) characterize their role in disease, and (3) survey the microbial diversity of the adenoid surface in children with a history of chronic infection. [NIH Grant DC00316]

Selected Publications

  • Berardi C, Larson N, Decker P, Wassel C, Kirsch P, Pankow J, Sale M, de Andrade M, Sicotte H, Tang W, Hanson N, Tsai M, Chen Y, Bielinski S. Multi-ethnic analysis reveals soluble L-selectin may be post-transcriptionally regulated by 3'UTR polymorphism: the Multi-Ethnic Study of Atherosclerosis (MESA). Human genetics. 2015. PMID: 25576479
  • Allen E, Koeppel A, Hendley J, Turner S, Winther B, Sale M. Characterization of the nasopharyngeal microbiota in health and during rhinovirus challenge. Microbiome. 2014;2 22. PMID: 25028608 | PMCID: PMC4098959
  • Allen E, Manichaikul A, Chen W, Rich S, Daly K, Sale M. Evaluation of replication of variants associated with genetic risk of otitis media. PloS one. 2014;9(8): e104212. PMID: 25089819 | PMCID: PMC4121324
  • Allen E, Manichaikul A, Sale M. Genetic contributors to otitis media: agnostic discovery approaches. Current allergy and asthma reports. 2014;14(2): 411. PMID: 24415464
  • Berardi C, Decker P, Kirsch P, de Andrade M, Tsai M, Pankow J, Sale M, Sicotte H, Tang W, Hanson N, Polak J, Bielinski S. Plasma and serum L-selectin and clinical and subclinical cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA). Translational research : the journal of laboratory and clinical medicine. 2014;163(6): 585-92. PMID: 24631064 | PMCID: PMC4029851
  • Huang J, Huffman J, Yamakuchi M, Yamkauchi M, Trompet S, Asselbergs F, Sabater-Lleal M, Trégouët D, Chen W, Smith N, Kleber M, Shin S, Becker D, Tang W, Dehghan A, Johnson A, Truong V, Folkersen L, Yang Q, Oudot-Mellkah T, Buckley B, Moore J, Williams F, Campbell H, Silbernagel G, Vitart V, Rudan I, Tofler G, Navis G, Destefano A, Wright A, Chen M, de Craen A, Worrall B, Rudnicka A, Rumley A, Bookman E, Psaty B, Chen F, Keene K, Franco O, Böhm B, Uitterlinden A, Carter A, Jukema J, Sattar N, Bis J, Ikram M, Sale M, McKnight B, Fornage M, Ford I, Taylor K, Slagboom P, McArdle W, Hsu F, Franco-Cereceda A, Goodall A, Yanek L, Furie K, Cushman M, Hofman A, Witteman J, Folsom A, Basu S, Matijevic N, van Gilst W, Wilson J, Westendorp R, Kathiresan S, Reilly M, Tracy R, Polasek O, Winkelmann B, Grant P, Hillege H, Cambien F, Stott D, Lowe G, Spector T, Meigs J, Marz W, Eriksson P, Becker L, Morange P, Soranzo N, Williams S, Hayward C, van der Harst P, Hamsten A, Lowenstein C, Strachan D, O'Donnell C. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, thrombosis, and vascular biology. 2014;34(5): 1093-101. PMID: 24578379 | PMCID: PMC4009733
  • Hunt K, Kistner-Griffin E, Spruill I, Teklehaimanot A, Garvey W, Sale M, Fernandes J. Cardiovascular risk in Gullah African Americans with high familial risk of type 2 diabetes mellitus: project SuGAR. Southern medical journal. 2014;107(10): 607-14. PMID: 25279862 | PMCID: PMC4215639
  • Keene K, Chen W, Chen F, Williams S, Elkhatib S, Hsu F, Mychaleckyj J, Doheny K, Pugh E, Ling H, Laurie C, Gogarten S, Madden E, Worrall B, Sale M. Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial. Frontiers in public health. 2014;2 112. PMID: 25147783 | PMCID: PMC4123605
  • Kilarski L, Achterberg S, Devan W, Traylor M, Malik R, Lindgren A, Pare G, Sharma P, Slowik A, Thijs V, Walters M, Worrall B, Sale M, Algra A, Kappelle L, Wijmenga C, Norrving B, Sandling J, Rönnblom L, Goris A, Franke A, Sudlow C, Rothwell P, Levi C, Holliday E, Fornage M, Psaty B, Gretarsdottir S, Thorsteinsdottir U, Seshadri S, Mitchell B, Kittner S, Clarke R, Hopewell J, Bis J, Boncoraglio G, Meschia J, Ikram M, Hansen B, Montaner J, Thorleifsson G, Stefanson K, Rosand J, de Bakker P, Farrall M, Dichgans M, Markus H, Bevan S. Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12. Neurology. 2014;83(8): 678-85. PMID: 25031287 | PMCID: PMC4150131
  • Ng M, Shriner D, Chen B, Li J, Chen W, Guo X, Liu J, Bielinski S, Yanek L, Nalls M, Comeau M, Rasmussen-Torvik L, Jensen R, Evans D, Sun Y, An P, Patel S, Lu Y, Long J, Armstrong L, Wagenknecht L, Yang L, Snively B, Palmer N, Mudgal P, Langefeld C, Keene K, Freedman B, Mychaleckyj J, Nayak U, Raffel L, Goodarzi M, Chen Y, Taylor H, Correa A, Sims M, Couper D, Pankow J, Boerwinkle E, Adeyemo A, Doumatey A, Chen G, Mathias R, Vaidya D, Singleton A, Zonderman A, Igo R, Sedor J, Kabagambe E, Siscovick D, McKnight B, Rice K, Liu Y, Hsueh W, Zhao W, Bielak L, Kraja A, Province M, Bottinger E, Gottesman O, Cai Q, Zheng W, Blot W, Lowe W, Pacheco J, Crawford D, Grundberg E, Rich S, Hayes M, Shu X, Loos R, Borecki I, Peyser P, Cummings S, Psaty B, Fornage M, Iyengar S, Evans M, Becker D, Kao W, Wilson J, Rotter J, Sale M, Liu S, Rotimi C, Bowden D. Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS genetics. 2014;10(8): e1004517. PMID: 25102180 | PMCID: PMC4125087
  • Wakefield J, Skrivankova V, Hsu F, Sale M, Heagerty P. Detecting signals in pharmacogenomic genome-wide association studies. The pharmacogenomics journal. 2014;14(4): 309-15. PMID: 24394200 | PMCID: PMC4085158
  • Williams S, Yang Q, Chen F, Liu X, Keene K, Jacques P, Chen W, Weinstein G, Hsu F, Beiser A, Wang L, Bookman E, Doheny K, Wolf P, Zilka M, Selhub J, Nelson S, Gogarten S, Worrall B, Seshadri S, Sale M. Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. PLoS genetics. 2014;10(3): e1004214. PMID: 24651765 | PMCID: PMC3961178
  • Zhu X, Feng T, Tayo B, Liang J, Young J, Franceschini N, Smith J, Yanek L, Sun Y, Edwards T, Chen W, Nalls M, Fox E, Sale M, Bottinger E, Rotimi C, Liu Y, McKnight B, Liu K, Arnett D, Chakravati A, Cooper R, Redline S. Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension. American journal of human genetics. 2014;96(1): 21-36. PMID: 25500260 | PMCID: PMC4289691
  • Allen E, Chen W, Weeks D, Chen F, Hou X, Mattos J, Mychaleckyj J, Segade F, Casselbrant M, Mandel E, Ferrell R, Rich S, Daly K, Sale M. A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2. Journal of the Association for Research in Otolaryngology : JARO. 2013;14(6): 791-800. PMID: 23974705 | PMCID: PMC3825021
  • Franceschini N, Fox E, Zhang Z, Edwards T, Nalls M, Sung Y, Tayo B, Sun Y, Gottesman O, Adeyemo A, Johnson A, Young J, Rice K, Duan Q, Chen F, Li Y, Tang H, Fornage M, Keene K, Andrews J, Smith J, Faul J, Guangfa Z, Guo W, Liu Y, Murray S, Musani S, Srinivasan S, Velez Edwards D, Wang H, Becker L, Bovet P, Bochud M, Broeckel U, Burnier M, Carty C, Chasman D, Ehret G, Chen W, Chen G, Chen W, Ding J, Dreisbach A, Evans M, Guo X, Garcia M, Jensen R, Keller M, Lettre G, Lotay V, Martin L, Moore J, Morrison A, Mosley T, Ogunniyi A, Palmas W, Papanicolaou G, Penman A, Polak J, Ridker P, Salako B, Singleton A, Shriner D, Taylor K, Vasan R, Wiggins K, Williams S, Yanek L, Zhao W, Zonderman A, Becker D, Berenson G, Boerwinkle E, Bottinger E, Cushman M, Eaton C, Nyberg F, Heiss G, Hirschhron J, Howard V, Karczewsk K, Lanktree M, Liu K, Liu Y, Loos R, Margolis K, Snyder M, Psaty B, Schork N, Weir D, Rotimi C, Sale M, Harris T, Kardia S, Hunt S, Arnett D, Redline S, Cooper R, Risch N, Rao D, Rotter J, Chakravarti A, Reiner A, Levy D, Keating B, Zhu X. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. American journal of human genetics. 2013;93(3): 545-54. PMID: 23972371 | PMCID: PMC3769920
  • Liu C, Monda K, Taylor K, Lange L, Demerath E, Palmas W, Wojczynski M, Ellis J, Vitolins M, Liu S, Papanicolaou G, Irvin M, Xue L, Griffin P, Nalls M, Adeyemo A, Liu J, Li G, Ruiz-Narvaez E, Chen W, Chen F, Henderson B, Millikan R, Ambrosone C, Strom S, Guo X, Andrews J, Sun Y, Mosley T, Yanek L, Shriner D, Haritunians T, Rotter J, Speliotes E, Smith M, Rosenberg L, Mychaleckyj J, Nayak U, Spruill I, Garvey W, Pettaway C, Nyante S, Bandera E, Britton A, Zonderman A, Rasmussen-Torvik L, Chen Y, Ding J, Lohman K, Kritchevsky S, Zhao W, Peyser P, Kardia S, Kabagambe E, Broeckel U, Chen G, Zhou J, Wassertheil-Smoller S, Neuhouser M, Rampersaud E, Psaty B, Kooperberg C, Manson J, Kuller L, Ochs-Balcom H, Johnson K, Sucheston L, Ordovas J, Palmer J, Haiman C, McKnight B, Howard B, Becker D, Bielak L, Liu Y, Allison M, Grant S, Burke G, Patel S, Schreiner P, Borecki I, Evans M, Taylor H, Sale M, Howard V, Carlson C, Rotimi C, Cushman M, Harris T, Reiner A, Cupples L, North K, Fox C. Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS genetics. 2013;9(8): e1003681. PMID: 23966867 | PMCID: PMC3744443
  • Monda K, Chen G, Taylor K, Palmer C, Edwards T, Lange L, Ng M, Adeyemo A, Allison M, Bielak L, Chen G, Graff M, Irvin M, Rhie S, Li G, Liu Y, Liu Y, Lu Y, Nalls M, Sun Y, Wojczynski M, Yanek L, Aldrich M, Ademola A, Amos C, Bandera E, Bock C, Britton A, Broeckel U, Cai Q, Caporaso N, Carlson C, Carpten J, Casey G, Chen W, Chen F, Chen Y, Chiang C, Coetzee G, Demerath E, Deming-Halverson S, Driver R, Dubbert P, Feitosa M, Feng Y, Freedman B, Gillanders E, Gottesman O, Guo X, Haritunians T, Harris T, Harris C, Hennis A, Hernandez D, McNeill L, Howard T, Howard B, Howard V, Johnson K, Kang S, Keating B, Kolb S, Kuller L, Kutlar A, Langefeld C, Lettre G, Lohman K, Lotay V, Lyon H, Manson J, Maixner W, Meng Y, Monroe K, Morhason-Bello I, Murphy A, Mychaleckyj J, Nadukuru R, Nathanson K, Nayak U, N'diaye A, Nemesure B, Wu S, Leske M, Neslund-Dudas C, Neuhouser M, Nyante S, Ochs-Balcom H, Ogunniyi A, Ogundiran T, Ojengbede O, Olopade O, Palmer J, Ruiz-Narvaez E, Palmer N, Press M, Rampersaud E, Rasmussen-Torvik L, Rodriguez-Gil J, Salako B, Schadt E, Schwartz A, Shriner D, Siscovick D, Smith S, Wassertheil-Smoller S, Speliotes E, Spitz M, Sucheston L, Taylor H, Tayo B, Tucker M, Van Den Berg D, Edwards D, Wang Z, Wiencke J, Winkler T, Witte J, Wrensch M, Wu X, Yang J, Levin A, Young T, Zakai N, Cushman M, Zanetti K, Zhao J, Zhao W, Zheng Y, Zhou J, Ziegler R, Zmuda J, Fernandes J, Gilkeson G, Kamen D, Hunt K, Spruill I, Ambrosone C, Ambs S, Arnett D, Atwood L, Becker D, Berndt S, Bernstein L, Blot W, Borecki I, Bottinger E, Bowden D, Burke G, Chanock S, Cooper R, Ding J, Duggan D, Evans M, Fox C, Garvey W, Bradfield J, Hakonarson H, Grant S, Hsing A, Chu L, Hu J, Huo D, Ingles S, John E, Jordan J, Kabagambe E, Kardia S, Kittles R, Goodman P, Klein E, Kolonel L, Le Marchand L, Liu S, McKnight B, Millikan R, Mosley T, Padhukasahasram B, Williams L, Patel S, Peters U, Pettaway C, Peyser P, Psaty B, Redline S, Rotimi C, Rybicki B, Sale M, Schreiner P, Signorello L, Singleton A, Stanford J, Strom S, Thun M, Vitolins M, Zheng W, Moore J, Williams S, Ketkar S, Zhu X, Zonderman A, Kooperberg C, Papanicolaou G, Henderson B, Reiner A, Hirschhorn J, Loos R, North K, Haiman C. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature genetics. 2013;45(6): 690-6. PMID: 23583978 | PMCID: PMC3694490
  • Yadav S, Cotlarciuc I, Munroe P, Khan M, Nalls M, Bevan S, Cheng Y, Chen W, Malik R, McCarthy N, Holliday E, Speed D, Hasan N, Pucek M, Rinne P, Sever P, Stanton A, Shields D, Maguire J, McEvoy M, Scott R, Ferrucci L, Macleod M, Attia J, Markus H, Sale M, Worrall B, Mitchell B, Dichgans M, Sudlow C, Meschia J, Rothwell P, Caulfield M, Sharma P. Genome-wide analysis of blood pressure variability and ischemic stroke. Stroke; a journal of cerebral circulation. 2013;44(10): 2703-9. PMID: 23929743 | PMCID: PMC3904673
  • Cheng Y, Anderson C, Bione S, Keene K, Maguire J, Nalls M, Rasheed A, Zeginigg M, Attia J, Baker R, Barlera S, Biffi A, Bookman E, Brott T, Brown R, Chen F, Chen W, Ciusani E, Cole J, Cortellini L, Danesh J, Doheny K, Ferrucci L, Grazia Franzosi M, Frossard P, Furie K, Golledge J, Hankey G, Hernandez D, Holliday E, Hsu F, Jannes J, Kamal A, Khan M, Kittner S, Koblar S, Lewis M, Lincz L, Lisa A, Matarin M, Moscato P, Mychaleckyj J, Parati E, Parolo S, Pugh E, Rost N, Schallert M, Schmidt H, Scott R, Sturm J, Yadav S, Zaidi M, Boncoraglio G, Levi C, Meschia J, Rosand J, Sale M, Saleheen D, Schmidt R, Sharma P, Worrall B, Mitchell B. Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke; a journal of cerebral circulation. 2012;43(4): 980-6. PMID: 22363065 | PMCID: PMC3622211
  • Elbers C, Guo Y, Tragante V, van Iperen E, Lanktree M, Castillo B, Chen F, Yanek L, Wojczynski M, Li Y, Ferwerda B, Ballantyne C, Buxbaum S, Chen Y, Chen W, Cupples L, Cushman M, Duan Y, Duggan D, Evans M, Fernandes J, Fornage M, Garcia M, Garvey W, Glazer N, Gomez F, Harris T, Halder I, Howard V, Keller M, Kamboh M, Kooperberg C, Kritchevsky S, LaCroix A, Liu K, Liu Y, Musunuru K, Newman A, Onland-Moret N, Ordovas J, Peter I, Post W, Redline S, Reis S, Saxena R, Schreiner P, Volcik K, Wang X, Yusuf S, Zonderland A, Anand S, Becker D, Psaty B, Rader D, Reiner A, Rich S, Rotter J, Sale M, Tsai M, Borecki I, Hegele R, Kathiresan S, Nalls M, Taylor H, Hakonarson H, Sivapalaratnam S, Asselbergs F, Drenos F, Wilson J, Keating B. Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. PloS one. 2012;7(12): e50198. PMID: 23236364 | PMCID: PMC3517599
  • Frazier-Wood A, Manichaikul A, Aslibekyan S, Borecki I, Goff D, Hopkins P, Lai C, Ordovas J, Post W, Rich S, Sale M, Siscovick D, Straka R, Tiwari H, Tsai M, Rotter J, Arnett D. Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity. Human genetics. 2012;132(4): 405-13. PMID: 23263444 | PMCID: PMC3600091
  • Lutsey P, Wassel C, Cushman M, Sale M, Divers J, Folsom A. Genetic admixture is associated with plasma hemostatic factor levels in self-identified African Americans and Hispanics: the Multi-Ethnic Study of Atherosclerosis. Journal of thrombosis and haemostasis : JTH. 2012;10(4): 543-9. PMID: 22332961 | PMCID: PMC3361899
  • Manichaikul A, Palmas W, Rodriguez C, Peralta C, Divers J, Guo X, Chen W, Wong Q, Williams K, Kerr K, Taylor K, Tsai M, Goodarzi M, Sale M, Diez-Roux A, Rich S, Rotter J, Mychaleckyj J. Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis. PLoS genetics. 2012;8(4): e1002640. PMID: 22511882 | PMCID: PMC3325201
  • Palmer N, McDonough C, Hicks P, Roh B, Wing M, An S, Hester J, Cooke J, Bostrom M, Rudock M, Talbert M, Lewis J, Ferrara A, Lu L, Ziegler J, Sale M, Divers J, Shriner D, Adeyemo A, Rotimi C, Ng M, Langefeld C, Freedman B, Bowden D, Voight B, Scott L, Steinthorsdottir V, Morris A, Dina C, Welch R, Zeggini E, Huth C, Aulchenko Y, Thorleifsson G, McCulloch L, Ferreira T, Grallert H, Amin N, Wu G, Willer C, Raychaudhuri S, McCarroll S, Langenberg C, Hofmann O, Dupuis J, Qi L, Segrè A, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett A, Blagieva R, Boerwinkle E, Bonnycastle L, Boström K, Bravenboer B, Bumpstead S, Burtt N, Charpentier G, Chines P, Cornelis M, Couper D, Crawford G, Doney A, Elliott K, Elliott A, Erdos M, Fox C, Franklin C, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves C, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson A, Johnson P, Jørgensen T, Kao W, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren C, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken M, Narisu N, Nilsson P, Owen K, Payne F, Perry J, Petersen A, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner N, Robertson N, Rocheleau G, Roden M, Sampson M, Saxena R, Shields B, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham H, Sun Q, Swift A, Thorand B, Tichet J, Tuomi T, van Dam R, van Haeften T, van Herpt T, van Vliet-Ostaptchouk J, Walters G, Weedon M, Wijmenga C, Witteman J, Bergman R, Cauchi S, Collins F, Gloyn A, Gyllensten U, Hansen T, Hide W, Hitman G, Hofman A, Hunter D, Hveem K, Laakso M, Mohlke K, Morris A, Palmer C, Pramstaller P, Rudan I, Sijbrands E, Stein L, Tuomilehto J, Uitterlinden A, Walker M, Wareham N, Watanabe R, Abecasis G, Boehm B, Campbell H, Daly M, Hattersley A, Hu F, Meigs J, Pankow J, Pedersen O, Wichmann H, Barroso I, Florez J, Frayling T, Groop L, Sladek R, Thorsteinsdottir U, Wilson J, Illig T, Froguel P, van Duijn C, Stefansson K, Altshuler D, Boehnke M, McCarthy M, Soranzo N, Wheeler E, Glazer N, Bouatia-Naji N, Mägi R, Randall J, Johnson T, Elliott P, Rybin D, Henneman P, Dehghan A, Hottenga J, Song K, Goel A, Egan J, Lajunen T, Doney A, Kanoni S, Cavalcanti-Proença C, Kumari M, Timpson N, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll S, Roccasecca R, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby J, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead S, Chen Y, Chines P, Clarke R, Coin L, Cooper M, Crisponi L, Day I, de Geus E, Delplanque J, Fedson A, Fischer-Rosinsky A, Forouhi N, Frants R, Franzosi M, Galan P, Goodarzi M, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen A, Hayward C, Heath S, Hercberg S, Hicks A, Hillman D, Hingorani A, Hui J, Hung J, Jula A, Kaakinen M, Kaprio J, Kesaniemi Y, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik K, Lathrop G, Lawlor D, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Manning A, Martínez-Larrad M, McAteer J, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell B, Mukherjee S, Naitza S, Neville M, Oostra B, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden J, Pedersen N, Perola M, Pfeiffer A, Pichler I, Polasek O, Posthuma D, Potter S, Pouta A, Province M, Psaty B, Rayner N, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer A, Scheet P, Seedorf U, Sharp S, Shields B, Sijbrands E, Silveira A, Simpson L, Singleton A, Smith N, Sovio U, Swift A, Syddall H, Syvänen A, Tanaka T, Tönjes A, Uitterlinden A, van Dijk K, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner P, Walley A, Ward K, Watkins H, Wild S, Willemsen G, Witteman J, Yarnell J, Zelenika D, Zethelius B, Zhai G, Zhao J, Zillikens M, Borecki I, Loos R, Meneton P, Magnusson P, Nathan D, Williams G, Silander K, Salomaa V, Smith G, Bornstein S, Schwarz P, Spranger J, Karpe F, Shuldiner A, Cooper C, Dedoussis G, Serrano-Ríos M, Lind L, Palmer L, Franks P, Ebrahim S, Marmot M, Kao W, Pramstaller P, Wright A, Stumvoll M, Hamsten A, Buchanan T, Valle T, Rotter J, Siscovick D, Penninx B, Boomsma D, Deloukas P, Spector T, Ferrucci L, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin M, Waterworth D, Vollenweider P, Peltonen L, Mooser V, Sladek R. A genome-wide association search for type 2 diabetes genes in African Americans. PloS one. 2012;7(1): e29202. PMID: 22238593 | PMCID: PMC3251563
  • Rasmussen-Torvik L, Guo X, Bowden D, Bertoni A, Sale M, Yao J, Bluemke D, Goodarzi M, Chen Y, Vaidya D, Raffel L, Papanicolaou G, Meigs J, Pankow J. Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA). Genetic epidemiology. 2012;36(4): 384-91. PMID: 22508271 | PMCID: PMC3507617
  • Ren T, Glatt D, Nguyen T, Allen E, Early S, Sale M, Winther B, Wu M. 16S rRNA survey revealed complex bacterial communities and evidence of bacterial interference on human adenoids. Environmental microbiology. 2012;15(2): 535-47. PMID: 23113966
  • Traylor M, Farrall M, Holliday E, Sudlow C, Hopewell J, Cheng Y, Fornage M, Ikram M, Malik R, Bevan S, Thorsteinsdottir U, Nalls M, Longstreth W, Wiggins K, Yadav S, Parati E, Destefano A, Worrall B, Kittner S, Khan M, Reiner A, Helgadottir A, Achterberg S, Fernandez-Cadenas I, Abboud S, Schmidt R, Walters M, Chen W, Ringelstein E, O'Donnell M, Ho W, Pera J, Lemmens R, Norrving B, Higgins P, Benn M, Sale M, Kuhlenbäumer G, Doney A, Vicente A, Delavaran H, Algra A, Davies G, Oliveira S, Palmer C, Deary I, Schmidt H, Pandolfo M, Montaner J, Carty C, de Bakker P, Kostulas K, Ferro J, van Zuydam N, Valdimarsson E, Nordestgaard B, Lindgren A, Thijs V, Slowik A, Saleheen D, Paré G, Berger K, Thorleifsson G, Hofman A, Mosley T, Mitchell B, Furie K, Clarke R, Levi C, Seshadri S, Gschwendtner A, Boncoraglio G, Sharma P, Bis J, Gretarsdottir S, Psaty B, Rothwell P, Rosand J, Meschia J, Stefansson K, Dichgans M, Markus H. Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. The Lancet. Neurology. 2012;11(11): 951-62. PMID: 23041239 | PMCID: PMC3490334
  • Chen W, Allen E, Mychaleckyj J, Chen F, Hou X, Rich S, Daly K, Sale M. Significant linkage at chromosome 19q for otitis media with effusion and/or recurrent otitis media (COME/ROM). BMC medical genetics. 2011;12 124. PMID: 21943191 | PMCID: PMC3191346
  • Hsu F, Sides E, Mychaleckyj J, Worrall B, Elias G, Liu Y, Chen W, Coull B, Toole J, Rich S, Furie K, Sale M. Transcobalamin 2 variant associated with poststroke homocysteine modifies recurrent stroke risk. Neurology. 2011;77(16): 1543-50. PMID: 21975197 | PMCID: PMC3198974
  • Manichaikul A, Chen W, Williams K, Wong Q, Sale M, Pankow J, Tsai M, Rotter J, Rich S, Mychaleckyj J. Analysis of family- and population-based samples in cohort genome-wide association studies. Human genetics. 2011;131(2): 275-87. PMID: 21805149 | PMCID: PMC3369696
  • Sale M, Chen W, Weeks D, Mychaleckyj J, Hou X, Marion M, Segade F, Casselbrant M, Mandel E, Ferrell R, Rich S, Daly K. Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM). PloS one. 2011;6(8): e22297. PMID: 21857919 | PMCID: PMC3156706
  • Tzeng J, Zhang D, Pongpanich M, Smith C, McCarthy M, Sale M, Worrall B, Hsu F, Thomas D, Sullivan P. Studying gene and gene-environment effects of uncommon and common variants on continuous traits: a marker-set approach using gene-trait similarity regression. American journal of human genetics. 2011;89(2): 277-88. PMID: 21835306 | PMCID: PMC3155192
  • Leak T, Langefeld C, Keene K, Gallagher C, Lu L, Mychaleckyj J, Rich S, Freedman B, Bowden D, Sale M. Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy. BMC medical genetics. 2010;11 22. PMID: 20144192 | PMCID: PMC2829011
  • Manichaikul A, Mychaleckyj J, Rich S, Daly K, Sale M, Chen W. Robust relationship inference in genome-wide association studies. Bioinformatics (Oxford, England). 2010;26(22): 2867-73. PMID: 20926424 | PMCID: PMC3025716
  • McDonough C, Palmer N, Hicks P, Roh B, An S, Cooke J, Hester J, Wing M, Bostrom M, Rudock M, Lewis J, Talbert M, Blevins R, Lu L, Ng M, Sale M, Divers J, Langefeld C, Freedman B, Bowden D. A genome-wide association study for diabetic nephropathy genes in African Americans. Kidney international. 2010;79(5): 563-72. PMID: 21150874 | PMCID: PMC3056271
  • Van Hee V, Adar S, Szpiro A, Barr R, Diez Roux A, Bluemke D, Sheppard L, Gill E, Bahrami H, Wassel C, Sale M, Siscovick D, Rotter J, Rich S, Kaufman J. Common genetic variation, residential proximity to traffic exposure, and left ventricular mass: the multi-ethnic study of atherosclerosis. Environmental health perspectives. 2010;118(7): 962-9. PMID: 20308035 | PMCID: PMC2920916
  • Borowiec M, Liew C, Thompson R, Boonyasrisawat W, Hu J, Mlynarski W, El Khattabi I, Kim S, Marselli L, Rich S, Krolewski A, Bonner-Weir S, Sharma A, Sale M, Mychaleckyj J, Kulkarni R, Doria A. Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(34): 14460-5. PMID: 19667185 | PMCID: PMC2732833
  • Divers J, Sale M, Lu L, Chen W, Lok K, Spruill I, Fernandes J, Langefeld C, Garvey W. The genetic architecture of lipoprotein subclasses in Gullah-speaking African American families enriched for type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR). Journal of lipid research. 2009;51(3): 586-97. PMID: 19783527 | PMCID: PMC2817588
  • Leak T, Perlegas P, Smith S, Keene K, Hicks P, Langefeld C, Mychaleckyj J, Rich S, Kirk J, Freedman B, Bowden D, Sale M. Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans. Annals of human genetics. 2009;73(2): 152-9. PMID: 19183347 | PMCID: PMC2778056
  • McGeachie M, Ramoni R, Mychaleckyj J, Furie K, Dreyfuss J, Liu Y, Herrington D, Guo X, Lima J, Post W, Rotter J, Rich S, Sale M, Ramoni M. Integrative predictive model of coronary artery calcification in atherosclerosis. Circulation. 2009;120(24): 2448-54. PMID: 19948975 | PMCID: PMC2810344
  • Sale M, Mychaleckyj J, Chen W. Planning and executing a genome wide association study (GWAS). Methods in molecular biology (Clifton, N.J.). 2009;590 403-18. PMID: 19763518
  • Dwyer T, Blizzard L, Patterson B, Ponsonby A, Martin K, Quinn S, Sale M, Richards S, Morley R, Rich S, Dickinson J. Association between birth weight and adolescent systolic blood pressure in a caucasian birth cohort differs according to skin type, CRH promoter or 11beta-HSD2 genotype. Archives of disease in childhood. 2008;93(9): 760-7. PMID: 18456686
  • Hicks P, Staten J, Palmer N, Langefeld C, Ziegler J, Keene K, Sale M, Bowden D, Freedman B. Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease. American journal of nephrology. 2008;28(6): 914-20. PMID: 18580054 | PMCID: PMC2786015
  • Keene K, Mychaleckyj J, Leak T, Smith S, Perlegas P, Divers J, Langefeld C, Freedman B, Bowden D, Sale M. Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease. Human genetics. 2008;124(2): 147-54. PMID: 18654799 | PMCID: PMC2786006
  • Keene K, Mychaleckyj J, Smith S, Leak T, Perlegas P, Langefeld C, Freedman B, Rich S, Bowden D, Sale M. Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes. 2008;57(4): 1057-62. PMID: 18184924
  • Keene K, Mychaleckyj J, Smith S, Leak T, Perlegas P, Langefeld C, Herrington D, Freedman B, Rich S, Bowden D, Sale M. Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population. Human genetics. 2008;123(4): 333-41. PMID: 18305958 | PMCID: PMC2752813
  • Leak T, Mychaleckyj J, Smith S, Keene K, Gordon C, Hicks P, Freedman B, Bowden D, Sale M. Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population. Human genetics. 2008;124(1): 63-71. PMID: 18560894 | PMCID: PMC2728933
  • Lewis J, Palmer N, Hicks P, Sale M, Langefeld C, Freedman B, Divers J, Bowden D. Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies. Diabetes. 2008;57(8): 2220-5. PMID: 18443202 | PMCID: PMC2494685
  • Ponsonby A, Blizzard L, Pezic A, Cochrane J, Ellis J, Morley R, Dickinson J, Sale M, Richards S, Dwyer T. Adiposity gain during childhood, ACE I/D polymorphisms and metabolic outcomes. Obesity (Silver Spring, Md.). 2008;16(9): 2141-7. PMID: 18551123
  • Ramoni R, Himes B, Sale M, Furie K, Ramoni M. Predictive genomics of cardioembolic stroke. Stroke; a journal of cerebral circulation. 2008;40(3): S67-70. PMID: 19064790 | PMCID: PMC2752697
  • Sale M, Lu L, Spruill I, Fernandes J, Lok K, Divers J, Langefeld C, Garvey W. Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR). Diabetes. 2008;58(1): 260-7. PMID: 18835935 | PMCID: PMC2606883
  • Freedman B, Hicks P, Sale M, Pierson E, Langefeld C, Rich S, Xu J, McDonough C, Janssen B, Yard B, van der Woude F, Bowden D. A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2007;22(4): 1131-5. PMID: 17205963
  • Gallagher C, Keene K, Mychaleckyj J, Langefeld C, Hirschhorn J, Henderson B, Gordon C, Freedman B, Rich S, Bowden D, Sale M. Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations. Diabetes. 2007;56(3): 675-84. PMID: 17327435
  • Gallagher C, Langefeld C, Gordon C, Campbell J, Mychaleckyj J, Mychalecky J, Bryer-Ash M, Rich S, Bowden D, Sale M. Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study. Diabetes. 2007;56(8): 2135-41. PMID: 17513703
  • Gudbjartsson D, Arnar D, Helgadottir A, Gretarsdottir S, Holm H, Sigurdsson A, Jonasdottir A, Baker A, Thorleifsson G, Kristjansson K, Palsson A, Blondal T, Sulem P, Backman V, Hardarson G, Palsdottir E, Helgason A, Sigurjonsdottir R, Sverrisson J, Kostulas K, Ng M, Baum L, So W, Wong K, Chan J, Furie K, Greenberg S, Sale M, Kelly P, MacRae C, Smith E, Rosand J, Hillert J, Ma R, Ellinor P, Thorgeirsson G, Gulcher J, Kong A, Thorsteinsdottir U, Stefansson K. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature. 2007;448(7151): 353-7. PMID: 17603472
  • Leak T, Keene K, Langefeld C, Gallagher C, Mychaleckyj J, Freedman B, Bowden D, Rich S, Sale M. Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population. Molecular genetics and metabolism. 2007;92(1): 145-50. PMID: 17618154 | PMCID: PMC2752824
  • Sale M, Hsu F, Palmer N, Gordon C, Keene K, Borgerink H, Sharma A, Bergman R, Taylor K, Saad M, Norris J. The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study. BMC endocrine disorders. 2007;7 1. PMID: 17397545 | PMCID: PMC1852562
  • Sale M, Rich S. Genetic contributions to type 2 diabetes: recent insights. Expert review of molecular diagnostics. 2007;7(2): 207-17. PMID: 17331067
  • Sale M, Smith S, Mychaleckyj J, Keene K, Langefeld C, Leak T, Hicks P, Bowden D, Rich S, Freedman B. Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes. 2007;56(10): 2638-42. PMID: 17601994
  • Dickinson J, Sale M, Passmore A, FitzGerald L, Wheatley C, Burdon K, Craig J, Tengtrisorn S, Carden S, Maclean H, Mackey D. Mutations in the NDP gene: contribution to Norrie disease, familial exudative vitreoretinopathy and retinopathy of prematurity. Clinical & experimental ophthalmology. 2006;34(7): 682-8. PMID: 16970763
  • Freedman B, Bowden D, Sale M, Langefeld C, Rich S. Genetic susceptibility contributes to renal and cardiovascular complications of type 2 diabetes mellitus. Hypertension. 2006;48(1): 8-13. PMID: 16735643
  • Sale M, Woods J, Freedman B. Genetic determinants of the metabolic syndrome. Current hypertension reports. 2006;8(1): 16-22. PMID: 16600155
  • Charlesworth J, Dyer T, Stankovich J, Blangero J, Mackey D, Craig J, Green C, Foote S, Baird P, Sale M. Linkage to 10q22 for maximum intraocular pressure and 1p32 for maximum cup-to-disc ratio in an extended primary open-angle glaucoma pedigree. Investigative ophthalmology & visual science. 2005;46(10): 3723-9. PMID: 16186355
  • Charlesworth J, Stankovich J, Mackey D, Craig J, Haybittel M, Westmore R, Sale M. Confirmation of the adult-onset primary open angle glaucoma locus GLC1B at 2cen-q13 in an Australian family. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde. 2005;220(1): 23-30. PMID: 16374045
  • Foote S, Rubio J, Bahlo M, Kilpatrick T, Speed T, Stankovich J, Burfoot R, Butzkueven H, Johnson L, Wilkinson C, Taylor B, Sale M, van der Mei I, Dickinson J, Groom P. Multiple sclerosis: a haplotype association study. Novartis Foundation symposium. 2005;267 31-9; discussion 39-45. PMID: 15999799
  • Freedman B, Bowden D, Rich S, Valis C, Sale M, Hicks P, Langefeld C. A genome scan for all-cause end-stage renal disease in African Americans. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2005;20(4): 712-8. PMID: 15701670
  • Freedman B, Rich S, Sale M, Heiss G, Djoussé L, Pankow J, Province M, Rao D, Lewis C, Chen Y, Beck S. Genome-wide scans for heritability of fasting serum insulin and glucose concentrations in hypertensive families. Diabetologia. 2005;48(4): 661-8. PMID: 15747111
  • Gallagher C, Gordon C, Langefeld C, Mychaleckyj J, Freedman B, Rich S, Bowden D, Sale M. Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population. Molecular genetics and metabolism. 2005;87(1): 54-60. PMID: 16140553
  • Sale M, Freedman B. Genetic determinants of albuminuria and renal disease in diabetes mellitus. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2005;21(1): 13-6. PMID: 16234290
  • Sale M, Freedman B, Hicks P, Williams A, Langefeld C, Gallagher C, Bowden D, Rich S. Loci contributing to adult height and body mass index in African American families ascertained for type 2 diabetes. Annals of human genetics. 2005;69 517-27. PMID: 16138910
  • Bowden D, Colicigno C, Langefeld C, Sale M, Williams A, Anderson P, Rich S, Freedman B. A genome scan for diabetic nephropathy in African Americans. Kidney international. 2004;66(4): 1517-26. PMID: 15458446
  • Burdon K, Wirth M, Mackey D, Russell-Eggitt I, Craig J, Elder J, Dickinson J, Sale M. A novel mutation in the Connexin 46 gene causes autosomal dominant congenital cataract with incomplete penetrance. Journal of medical genetics. 2004;41(8): e106. PMID: 15286166 | PMCID: PMC1735867
  • Dwyer T, Stankovich J, Blizzard L, FitzGerald L, Dickinson J, Reilly A, Williamson J, Ashbolt R, Berwick M, Sale M. Does the addition of information on genotype improve prediction of the risk of melanoma and nonmelanoma skin cancer beyond that obtained from skin phenotype? American journal of epidemiology. 2004;159(9): 826-33. PMID: 15105175
  • Freedman B, Langefeld C, Rich S, Valis C, Sale M, Williams A, Brown W, Beck S, Hicks P, Bowden D. A genome scan for ESRD in black families enriched for nondiabetic nephropathy. Journal of the American Society of Nephrology : JASN. 2004;15(10): 2719-27. PMID: 15466277
  • Sale M, Freedman B, Langefeld C, Williams A, Hicks P, Colicigno C, Beck S, Brown W, Rich S, Bowden D. A genome-wide scan for type 2 diabetes in African-American families reveals evidence for a locus on chromosome 6q. Diabetes. 2004;53(3): 830-7. PMID: 14988270
  • Sale M, Hazelwood K, Zimmet P, Shaw J, Stankovich J, Greenaway T, Dwyer T. Trends in diabetes management practices of patients from an Australian insulin-treated diabetes register. Diabetic medicine : a journal of the British Diabetic Association. 2004;21(2): 165-70. PMID: 14984452
  • Burdon K, McKay J, Sale M, Russell-Eggitt I, Mackey D, Wirth M, Elder J, Nicoll A, Clarke M, FitzGerald L, Stankovich J, Shaw M, Sharma S, Gajovic S, Gruss P, Ross S, Thomas P, Voss A, Thomas T, Gécz J, Craig J. Mutations in a novel gene, NHS, cause the pleiotropic effects of Nance-Horan syndrome, including severe congenital cataract, dental anomalies, and mental retardation. American journal of human genetics. 2003;73(5): 1120-30. PMID: 14564667 | PMCID: PMC1180491
  • Burdon K, Wilkinson R, Barbour J, Dickinson J, Stankovich J, Mackey D, Sale M. Investigation of albinism genes in congenital esotropia. Molecular vision. 2003;9 710-4. PMID: 14685142
  • Burdon K, Wirth M, Mackey D, Russell-Eggitt I, Craig J, Elder J, Dickinson J, Sale M. Investigation of crystallin genes in familial cataract, and report of two disease associated mutations. The British journal of ophthalmology. 2003;88(1): 79-83. PMID: 14693780 | PMCID: PMC1771940
  • Dwyer T, Sale M, Stankovich J, Hazelwood K, Mulcahy N. Using genetic advances to investigate diabetes in Tasmania. Diabetes technology & therapeutics. 2002;3(4): 641-6. PMID: 11911178
  • Rubio J, Bahlo M, Butzkueven H, van Der Mei I, Sale M, Dickinson J, Groom P, Johnson L, Simmons R, Tait B, Varney M, Taylor B, Dwyer T, Williamson R, Gough N, Kilpatrick T, Speed T, Foote S. Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis. American journal of human genetics. 2002;70(5): 1125-37. PMID: 11923913 | PMCID: PMC447590
  • Sale M, Craig J, Charlesworth J, FitzGerald L, Hanson I, Dickinson J, Matthews S, Heyningen Vv V, Fingert J, Mackey D. Broad phenotypic variability in a single pedigree with a novel 1410delC mutation in the PST domain of the PAX6 gene. Human mutation. 2002;20(4): 322. PMID: 12325030
  • Sale M, FitzGerald L, Charlesworth J, Bowden D, Rich S. Evidence for a novel type 1 diabetes susceptibility locus on chromosome 8. Diabetes. 2002;51 S316-9. PMID: 12475769
  • Sale M, FitzGerald L, Kagame K, Erdmann I, Craig J, Dickinson J, Cooper R. Investigation of the prevalence of the myocilin Q368STOP mutation in Ugandan glaucoma patients. Ophthalmic genetics. 2002;23(1): 67-9. PMID: 11910561
  • Stankovich J, Sale M, Cooley H, Bahlo M, Reilly A, Dickinson J, Jones G. Investigation of chromosome 2q in osteoarthritis of the hand: no significant linkage in a Tasmanian population. Annals of the rheumatic diseases. 2002;61(12): 1081-4. PMID: 12429539 | PMCID: PMC1753971
  • Wheatley C, Dickinson J, Mackey D, Craig J, Sale M. Retinopathy of prematurity: recent advances in our understanding. Archives of disease in childhood. Fetal and neonatal edition. 2002;87(2): F78-82. PMID: 12193510 | PMCID: PMC1721447
  • Wheatley C, Dickinson J, Mackey D, Craig J, Sale M. Retinopathy of prematurity: recent advances in our understanding. The British journal of ophthalmology. 2002;86(6): 696-700. PMID: 12034695 | PMCID: PMC1771164
  • Dickinson J, Sale M, Craig J, Mackey D. Laboratory methods in ophthalmic genetics: obtaining DNA from patients. Ophthalmic genetics. 2001;22(1): 49-60. PMID: 11262650
  • Akamizu T, Sale M, Rich S, Hiratani H, Noh J, Kanamoto N, Saijo M, Miyamoto Y, Saito Y, Nakao K, Bowden D. Association of autoimmune thyroid disease with microsatellite markers for the thyrotropin receptor gene and CTLA-4 in Japanese patients. Thyroid : official journal of the American Thyroid Association. 2000;10(10): 851-8. PMID: 11081251
  • Price J, Fossey S, Sale M, Brewer C, Freedman B, Wuerth J, Bowden D. Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients. Diabetologia. 2000;43(3): 364-72. PMID: 10768098
  • Price J, Brewer C, Howard T, Fossey S, Sale M, Ji L, Krolewski A, Bowden D. A physical map of the 20q12-q13.1 region associated with type 2 diabetes. Genomics. 1999;62(2): 208-15. PMID: 10610714
  • Yu H, Sale M, Rich S, Spray B, Roh B, Bowden D, Freedman B. Evaluation of markers on human chromosome 10, including the homologue of the rodent Rf-1 gene, for linkage to ESRD in black patients. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1999;33(2): 294-300. PMID: 10023641
  • Bowden D, Sale M, Howard T, Qadri A, Spray B, Rothschild C, Akots G, Rich S, Freedman B. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy. Diabetes. 1997;46(5): 882-6. PMID: 9133559
  • Sale M, Akamizu T, Howard T, Yokota T, Nakao K, Mori T, Iwasaki H, Rich S, Jennings-Gee J, Yamada M, Bowden D. Association of autoimmune thyroid disease with a microsatellite marker for the thyrotropin receptor gene and CTLA-4 in a Japanese population. Proceedings of the Association of American Physicians. 1997;109(5): 453-61. PMID: 9285944