Melissa M. Kendall


  • PhD, Portland State University

Primary Appointment

  • Assistant Professor, Microbiology, Immunology, and Cancer Biology


Research Interest(s)

Bacterial cell signaling, host-pathogen interactions, intestinal pathogens

Research Description

My research examines signaling pathways that enable bacterial pathogens to sense and adapt to specific niches within a host to cause disease. Our research focuses mainly on the intestinal pathogens, enterohemorrhagic Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium.

This research will improve our understanding of basic bacterial physiology and may lead to the development of anti-virulence therapies to treat infectious diseases.

Selected Publications

  • Kendall M, Sperandio V. What a Dinner Party! Mechanisms and Functions of Interkingdom Signaling in Host-Pathogen Associations. mBio. 2016;7(2): e01748. PMID: 26933054 | PMCID: PMC4810492
  • Luzader D, Willsey G, Wargo M, Kendall M. The ETT2-encoded regulator EtrB modulates enterohemorrhagic Escherichia coli virulence gene expression. Infection and immunity. 2016. PMID: 27324484
  • McKenney E, Kendall M. Microbiota and pathogen 'pas de deux': setting up and breaking down barriers to intestinal infection. Pathogens and disease. 2016;74(5). PMID: 27252177
  • Santiago A, Yan M, Tran M, Wright N, Luzader D, Kendall M, Ruiz-Perez F, Nataro J. A large family of anti-activators accompanying XylS/AraC family regulatory proteins. Molecular microbiology. 2016;101(2): 314-32. PMID: 27038276
  • Interkingdom Chemical Signaling in Enterohemorrhagic Escherichia coli O157:H7. Advances in experimental medicine and biology. 2015;874 201-13. PMID: 26589220
  • Anderson C, Clark D, Adli M, Kendall M. Ethanolamine Signaling Promotes Salmonella Niche Recognition and Adaptation during Infection. PLoS pathogens. 2015;11(11): e1005278. PMID: 26565973 | PMCID: PMC4643982
  • DuVall J, Borba J, Shafagati N, Luzader D, Shukla N, Li J, Kehn-Hall K, Kendall M, Feldman S, Landers J. Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens. PloS one. 2015;10(6): e0129830. PMID: 26068926 | PMCID: PMC4466016
  • Luzader D, Kendall M. Commensal 'trail of bread crumbs' provide pathogens with a map to the intestinal landscape. Current opinion in microbiology. 2015;29 68-73. PMID: 26707739 | PMCID: PMC4755895
  • Gonyar L, Kendall M. Ethanolamine and Choline Promote Expression of Putative and Characterized Fimbriae in Enterohemorrhagic Escherichia coli O157:H7. Infection and immunity. 2013;82(1): 193-201. PMID: 24126525 | PMCID: PMC3911853
  • Luzader D, Clark D, Gonyar L, Kendall M. EutR is a direct regulator of genes that contribute to metabolism and virulence in enterohemorrhagic Escherichia coli O157:H7. Journal of bacteriology. 2013;195(21): 4947-53. PMID: 23995630 | PMCID: PMC3807496
  • Kendall M, Gruber C, Parker C, Sperandio V. Ethanolamine controls expression of genes encoding components involved in interkingdom signaling and virulence in enterohemorrhagic Escherichia coli O157:H7. mBio. 2012;3(3). PMID: 22589288 | PMCID: PMC3372972
  • Kendall M, Gruber C, Rasko D, Hughes D, Sperandio V. Hfq virulence regulation in enterohemorrhagic Escherichia coli O157:H7 strain 86-24. Journal of bacteriology. 2011;193(24): 6843-51. PMID: 21984790 | PMCID: PMC3232842
  • Kendall M, Rasko D, Sperandio V. The LysR-type regulator QseA regulates both characterized and putative virulence genes in enterohaemorrhagic Escherichia coli O157:H7. Molecular microbiology. 2010;76(5): 1306-21. PMID: 20444105 | PMCID: PMC2936457
  • Vazquez-Juarez R, Kuriakose J, Rasko D, Ritchie J, Kendall M, Slater T, Sinha M, Luxon B, Popov V, Waldor M, Sperandio V, Torres A. CadA negatively regulates Escherichia coli O157:H7 adherence and intestinal colonization. Infection and immunity. 2008;76(11): 5072-81. PMID: 18794292 | PMCID: PMC2573373
  • Kendall M, Rasko D, Sperandio V. Global effects of the cell-to-cell signaling molecules autoinducer-2, autoinducer-3, and epinephrine in a luxS mutant of enterohemorrhagic Escherichia coli. Infection and immunity. 2007;75(10): 4875-84. PMID: 17635870 | PMCID: PMC2044543
  • Reading N, Torres A, Kendall M, Hughes D, Yamamoto K, Sperandio V. A novel two-component signaling system that activates transcription of an enterohemorrhagic Escherichia coli effector involved in remodeling of host actin. Journal of bacteriology. 2007;189(6): 2468-76. PMID: 17220220 | PMCID: PMC1899401
  • Kendall M, Boone D. Cultivation of methanogens from shallow marine sediments at Hydrate Ridge, Oregon. Archaea (Vancouver, B.C.). 2006;2(1): 31-8. PMID: 16877319 | PMCID: PMC2685590
  • Kendall M, Liu Y, Boone D. Butyrate- and propionate-degrading syntrophs from permanently cold marine sediments in Skan Bay, Alaska, and description of Algorimarina butyrica gen. nov., sp. nov. FEMS microbiology letters. 2006;262(1): 107-14. PMID: 16907746
  • Kendall M, Liu Y, Sieprawska-Lupa M, Stetter K, Whitman W, Boone D. Methanococcus aeolicus sp. nov., a mesophilic, methanogenic archaeon from shallow and deep marine sediments. International journal of systematic and evolutionary microbiology. 2006;56 1525-9. PMID: 16825624
  • Kendall M, Sperandio V. Quorum sensing by enteric pathogens. Current opinion in gastroenterology. 2006;23(1): 10-5. PMID: 17133078
  • Kendall M, Wardlaw G, Tang C, Bonin A, Liu Y, Valentine D. Diversity of Archaea in marine sediments from Skan Bay, Alaska, including cultivated methanogens, and description of Methanogenium boonei sp. nov. Applied and environmental microbiology. 2006;73(2): 407-14. PMID: 17122405 | PMCID: PMC1796967
  • Singh N, Kendall M, Liu Y, Boone D. Isolation and characterization of methylotrophic methanogens from anoxic marine sediments in Skan Bay, Alaska: description of Methanococcoides alaskense sp. nov., and emended description of Methanosarcina baltica. International journal of systematic and evolutionary microbiology. 2005;55 2531-8. PMID: 16280522