Melissa M. Kendall

Education

  • PhD, Portland State University

Primary Appointment

  • Assistant Professor, Microbiology, Immunology, and Cancer Biology

Contact

Research Interest(s)

Bacterial cell signaling, host-pathogen interactions, intestinal pathogens

Research Description

Chemical and nutrient signaling are fundamental for all cellular processes, including interactions between the mammalian host and the microbiota, which have a significant impact on health and disease. My lab is interested in understanding how bacterial pathogens exploit chemical and nutrient signaling to precisely regulate virulence gene expression to establish infection and cause disease. Elucidating these processes may enhance our arsenal of tools, such as new therapies or vaccines, to combat infectious diseases.

Selected Publications

  • Rowley C, Kendall M. To B12 or not to B12: Five questions on the role of cobalamin in host-microbial interactions. PLoS pathogens. 2019;15(1): e1007479. PMID: 30605490 | PMCID: PMC6317780
  • Anderson C, Satkovich J, Köseoğlu V, Agaisse H, Kendall M. The Ethanolamine Permease EutH Promotes Vacuole Adaptation of Salmonella enterica and Listeria monocytogenes during Macrophage Infection. Infection and immunity. 2018;86(5). PMID: 29531136 | PMCID: PMC5913834
  • Rowley C, Anderson C, Kendall M. Ethanolamine Influences Human Commensal Escherichia coli Growth, Gene Expression, and Competition with Enterohemorrhagic E. coli O157:H7. mBio. 2018;9(5). PMID: 30279284 | PMCID: PMC6168858
  • Sauder A, Kendall M. After the Fact(or): Posttranscriptional Gene Regulation in Enterohemorrhagic Escherichia coli O157:H7. Journal of bacteriology. 2018;200(19). PMID: 29967119 | PMCID: PMC6148468
  • Anderson C, Kendall M. Salmonella enterica Serovar Typhimurium Strategies for Host Adaptation. Frontiers in microbiology. 2017;8 1983. PMID: 29075247 | PMCID: PMC5643478
  • Kendall M, Sperandio V. What a Dinner Party! Mechanisms and Functions of Interkingdom Signaling in Host-Pathogen Associations. mBio. 2016;7(2): e01748. PMID: 26933054 | PMCID: PMC4810492
  • Luzader D, Willsey G, Wargo M, Kendall M. The ETT2-encoded regulator EtrB modulates enterohemorrhagic Escherichia coli virulence gene expression. Infection and immunity. 2016. PMID: 27324484
  • McKenney E, Kendall M. Microbiota and pathogen 'pas de deux': setting up and breaking down barriers to intestinal infection. Pathogens and disease. 2016;74(5). PMID: 27252177
  • Santiago A, Yan M, Tran M, Wright N, Luzader D, Kendall M, Ruiz-Perez F, Nataro J. A large family of anti-activators accompanying XylS/AraC family regulatory proteins. Molecular microbiology. 2016;101(2): 314-32. PMID: 27038276
  • Interkingdom Chemical Signaling in Enterohemorrhagic Escherichia coli O157:H7. Advances in experimental medicine and biology. 2015;874 201-13. PMID: 26589220
  • Anderson C, Clark D, Adli M, Kendall M. Ethanolamine Signaling Promotes Salmonella Niche Recognition and Adaptation during Infection. PLoS pathogens. 2015;11(11): e1005278. PMID: 26565973 | PMCID: PMC4643982
  • DuVall J, Borba J, Shafagati N, Luzader D, Shukla N, Li J, Kehn-Hall K, Kendall M, Feldman S, Landers J. Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens. PloS one. 2015;10(6): e0129830. PMID: 26068926 | PMCID: PMC4466016
  • Luzader D, Kendall M. Commensal 'trail of bread crumbs' provide pathogens with a map to the intestinal landscape. Current opinion in microbiology. 2015;29 68-73. PMID: 26707739 | PMCID: PMC4755895
  • Gonyar L, Kendall M. Ethanolamine and Choline Promote Expression of Putative and Characterized Fimbriae in Enterohemorrhagic Escherichia coli O157:H7. Infection and immunity. 2013;82(1): 193-201. PMID: 24126525 | PMCID: PMC3911853
  • Luzader D, Clark D, Gonyar L, Kendall M. EutR is a direct regulator of genes that contribute to metabolism and virulence in enterohemorrhagic Escherichia coli O157:H7. Journal of bacteriology. 2013;195(21): 4947-53. PMID: 23995630 | PMCID: PMC3807496
  • Kendall M, Gruber C, Parker C, Sperandio V. Ethanolamine controls expression of genes encoding components involved in interkingdom signaling and virulence in enterohemorrhagic Escherichia coli O157:H7. mBio. 2012;3(3). PMID: 22589288 | PMCID: PMC3372972
  • Kendall M, Gruber C, Rasko D, Hughes D, Sperandio V. Hfq virulence regulation in enterohemorrhagic Escherichia coli O157:H7 strain 86-24. Journal of bacteriology. 2011;193(24): 6843-51. PMID: 21984790 | PMCID: PMC3232842
  • Kendall M, Rasko D, Sperandio V. The LysR-type regulator QseA regulates both characterized and putative virulence genes in enterohaemorrhagic Escherichia coli O157:H7. Molecular microbiology. 2010;76(5): 1306-21. PMID: 20444105 | PMCID: PMC2936457
  • Vazquez-Juarez R, Kuriakose J, Rasko D, Ritchie J, Kendall M, Slater T, Sinha M, Luxon B, Popov V, Waldor M, Sperandio V, Torres A. CadA negatively regulates Escherichia coli O157:H7 adherence and intestinal colonization. Infection and immunity. 2008;76(11): 5072-81. PMID: 18794292 | PMCID: PMC2573373
  • Kendall M, Rasko D, Sperandio V. Global effects of the cell-to-cell signaling molecules autoinducer-2, autoinducer-3, and epinephrine in a luxS mutant of enterohemorrhagic Escherichia coli. Infection and immunity. 2007;75(10): 4875-84. PMID: 17635870 | PMCID: PMC2044543
  • Reading N, Torres A, Kendall M, Hughes D, Yamamoto K, Sperandio V. A novel two-component signaling system that activates transcription of an enterohemorrhagic Escherichia coli effector involved in remodeling of host actin. Journal of bacteriology. 2007;189(6): 2468-76. PMID: 17220220 | PMCID: PMC1899401
  • Kendall M, Boone D. Cultivation of methanogens from shallow marine sediments at Hydrate Ridge, Oregon. Archaea (Vancouver, B.C.). 2006;2(1): 31-8. PMID: 16877319 | PMCID: PMC2685590
  • Kendall M, Liu Y, Boone D. Butyrate- and propionate-degrading syntrophs from permanently cold marine sediments in Skan Bay, Alaska, and description of Algorimarina butyrica gen. nov., sp. nov. FEMS microbiology letters. 2006;262(1): 107-14. PMID: 16907746
  • Kendall M, Liu Y, Sieprawska-Lupa M, Stetter K, Whitman W, Boone D. Methanococcus aeolicus sp. nov., a mesophilic, methanogenic archaeon from shallow and deep marine sediments. International journal of systematic and evolutionary microbiology. 2006;56 1525-9. PMID: 16825624
  • Kendall M, Sperandio V. Quorum sensing by enteric pathogens. Current opinion in gastroenterology. 2006;23(1): 10-5. PMID: 17133078
  • Kendall M, Wardlaw G, Tang C, Bonin A, Liu Y, Valentine D. Diversity of Archaea in marine sediments from Skan Bay, Alaska, including cultivated methanogens, and description of Methanogenium boonei sp. nov. Applied and environmental microbiology. 2006;73(2): 407-14. PMID: 17122405 | PMCID: PMC1796967
  • Singh N, Kendall M, Liu Y, Boone D. Isolation and characterization of methylotrophic methanogens from anoxic marine sediments in Skan Bay, Alaska: description of Methanococcoides alaskense sp. nov., and emended description of Methanosarcina baltica. International journal of systematic and evolutionary microbiology. 2005;55 2531-8. PMID: 16280522