Loren D. Erickson

Education

  • BA, Seattle Pacific University
  • PhD, The University of Iowa
  • Postdoc, Dartmouth Medical School

Primary Appointment

  • Associate Professor, Microbiology, Immunology, and Cancer Biology

Contact

Research Interest(s)

Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus and multiple myeloma; Immunotherapeutics in the treatment of B cell disorders

Research Description

Selected Publications

  • Coquery C, Wade N, Loo W, Kinchen J, Cox K, Jiang C, Tung K, Erickson L. Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice. PloS one. 2014;9(7): e102284. PMID: 25010693 | PMCID: PMC4092127
  • Coquery C, Erickson L. Regulatory roles of the tumor necrosis factor receptor BCMA. Critical reviews in immunology. 2012;32(4): 287-305. PMID: 23237506 | PMCID: PMC3548317
  • Coquery C, Loo W, Buszko M, Lannigan J, Erickson L. Optimized protocol for the isolation of spleen-resident murine neutrophils. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2012;81(9): 806-14. PMID: 22760952 | PMCID: PMC3548322
  • Ernst P, Erickson L, Loo W, Scott K, Wiznerowicz E, Brown C, Torres-Velez F, Alam M, Black S, McDuffie M, Feldman S, Wallace J, McKnight G, Padol I, Hunt R, Tung K. Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice. American journal of physiology. Gastrointestinal and liver physiology. 2011;302(1): G105-15. PMID: 21921286 | PMCID: PMC3345967
  • Jiang C, Loo W, Greenley E, Tung K, Erickson L. B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus. Journal of immunology (Baltimore, Md. : 1950). 2011;186(11): 6136-47. PMID: 21536804 | PMCID: PMC3181142
  • Jørgensen T, Alfaro J, Enriquez H, Jiang C, Loo W, Atencio S, Bupp M, Mailloux C, Metzger T, Flannery S, Rozzo S, Kotzin B, Rosemblatt M, Bono M, Erickson L. Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus. Journal of immunology (Baltimore, Md. : 1950). 2009;184(2): 775-86. PMID: 20018631 | PMCID: PMC2841050
  • Khuda S, Loo W, Janz S, Van Ness B, Erickson L. Deregulation of c-Myc Confers distinct survival requirements for memory B cells, plasma cells, and their progenitors. Journal of immunology (Baltimore, Md. : 1950). 2008;181(11): 7537-49. PMID: 19017943 | PMCID: PMC2841033
  • Benson M, Erickson L, Gleeson M, Noelle R. Affinity of antigen encounter and other early B-cell signals determine B-cell fate. Current opinion in immunology. 2007;19(3): 275-80. PMID: 17433651 | PMCID: PMC2827202