Kwon-Sik Park

Primary Appointment

  • Assistant Professor, Microbiology, Immunology, and Cancer Biology

Contact

Research Interest(s)

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Research Description

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Selected Publications

  • George J, Lim J, Jang S, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan N, Park K, Yang D, Karnezis A, Vaka D, Torres A, Wang M, Korbel J, Menon R, Chun S, Kim D, Wilkerson M, Hayes N, Engelmann D, Pützer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmüller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel P, Petersen I, Chen Y, Soltermann A, Tischler V, Choi C, Kim Y, Massion P, Zou Y, Jovanovic D, Kontic M, Wright G, Russell P, Solomon B, Koch I, Lindner M, Muscarella L, la Torre A, Field J, Jakopovic M, Knezevic J, Castaños-Vélez E, Roz L, Pastorino U, Brustugun O, Lund-Iversen M, Thunnissen E, Köhler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen H, Achter V, Lang U, Bogus M, Schneider P, Zander T, Ansén S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis W, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas S, Brambilla E, Peifer M, Sage J, Thomas R. Comprehensive genomic profiles of small cell lung cancer. Nature. 2015;524(7563): 47-53. PMID: 26168399
  • Jahchan N, Dudley J, Mazur P, Flores N, Yang D, Palmerton A, Zmoos A, Vaka D, Tran K, Zhou M, Krasinska K, Riess J, Neal J, Khatri P, Park K, Butte A, Sage J. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer discovery. 2013;3(12): 1364-77. PMID: 24078773 | PMCID: PMC3864571
  • Peifer M, Fernández-Cuesta L, Sos M, George J, Seidel D, Kasper L, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus H, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann J, Lu X, Carter S, Cibulskis K, Banerji S, Getz G, Park K, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z, Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella L, Fazio V, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman D, Snijders P, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun O, Lund-Iversen M, Sänger J, Clement J, Soltermann A, Moch H, Weder W, Solomon B, Soria J, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider P, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Nürnberg P, Perner S, Heukamp L, Brindle P, Haas S, Thomas R. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nature genetics. 2012;44(10): 1104-10. PMID: 22941188
  • Park K, Liang M, Raiser D, Zamponi R, Roach R, Curtis S, Walton Z, Schaffer B, Roake C, Zmoos A, Kriegel C, Wong K, Sage J, Kim C. Characterization of the cell of origin for small cell lung cancer. Cell cycle (Georgetown, Tex.). 2011;10(16): 2806-15. PMID: 21822053 | PMCID: PMC3219544
  • Park K, Martelotto L, Peifer M, Sos M, Karnezis A, Mahjoub M, Bernard K, Conklin J, Szczepny A, Yuan J, Guo R, Ospina B, Falzon J, Bennett S, Brown T, Markovic A, Devereux W, Ocasio C, Chen J, Stearns T, Thomas R, Dorsch M, Buonamici S, Watkins D, Peacock C, Sage J. A crucial requirement for Hedgehog signaling in small cell lung cancer. Nature medicine. 2011;17(11): 1504-8. PMID: 21983857 | PMCID: PMC3380617
  • Schaffer B, Park K, Yiu G, Conklin J, Lin C, Burkhart D, Karnezis A, Sweet-Cordero E, Sage J. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer research. 2010;70(10): 3877-83. PMID: 20406986 | PMCID: PMC2873158