Kenneth S. Tung

Education

  • MBBS, Melbourne University, Melbourne, Australia
  • Resident, Melbourne University, Melbourne, Australia
  • Resident, Cleveland Clinic, Cleveland, Ohio
  • Fellowship, Scripps Clinic & Res. Fdn., La Jolla, CA

Primary Appointment

  • Professor, Pathology

Contact

Research Interest(s)

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Research Description

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Selected Publications

  • Coquery C, Wade N, Loo W, Kinchen J, Cox K, Jiang C, Tung K, Erickson L. Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice. PloS one. 2014;9(7): e102284. PMID: 25010693 | PMCID: PMC4092127
  • Rival C, Wheeler K, Jeffrey S, Qiao H, Luu B, Tewalt E, Engelhard V, Tardif S, Hardy D, del Rio R, Teuscher C, Tung K. Regulatory T cells and vasectomy. Journal of reproductive immunology. 2013;100(1): 66-75. PMID: 24080233 | PMCID: PMC3965253
  • Mauldin I, Tung K, Lorenz U. The tyrosine phosphatase SHP-1 dampens murine Th17 development. Blood. 2012;119(19): 4419-29. PMID: 22438258 | PMCID: PMC3362360
  • Tewalt E, Cohen J, Rouhani S, Guidi C, Qiao H, Fahl S, Conaway M, Bender T, Tung K, Vella A, Adler A, Chen L, Engelhard V. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood. 2012. PMID: 22993390 | PMCID: PMC3520619
  • Carroll V, Lundgren A, Wei H, Sainz S, Tung K, Brown M. Natural killer cells regulate murine cytomegalovirus-induced sialadenitis and salivary gland disease. Journal of virology. 2011;86(4): 2132-42. PMID: 22156514 | PMCID: PMC3302420
  • Ernst P, Erickson L, Loo W, Scott K, Wiznerowicz E, Brown C, Torres-Velez F, Alam M, Black S, McDuffie M, Feldman S, Wallace J, McKnight G, Padol I, Hunt R, Tung K. Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice. American journal of physiology. Gastrointestinal and liver physiology. 2011;302(1): G105-15. PMID: 21921286 | PMCID: PMC3345967
  • Ernst P, Wiznerowicz E, Feldman S, Tung K. Pathogenesis of gastritis in ileitis-prone SAMP1/Yit mice. The Keio journal of medicine. 2011;60(2): 65-8. PMID: 21720202
  • Jiang C, Loo W, Greenley E, Tung K, Erickson L. B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus. Journal of immunology (Baltimore, Md. : 1950). 2011;186(11): 6136-47. PMID: 21536804 | PMCID: PMC3181142
  • Wheeler K, Tardif S, Rival C, Luu B, Bui E, Del Rio R, Teuscher C, Sparwasser T, Hardy D, Tung K. Regulatory T cells control tolerogenic versus autoimmune response to sperm in vasectomy. Proceedings of the National Academy of Sciences of the United States of America. 2011;108(18): 7511-6. PMID: 21502500 | PMCID: PMC3088630
  • Cohen J, Guidi C, Tewalt E, Qiao H, Rouhani S, Ruddell A, Farr A, Tung K, Engelhard V. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. The Journal of experimental medicine. 2010;207(4): 681-8. PMID: 20308365 | PMCID: PMC2856027
  • Case L, Del Rio R, Bonney E, Zachary J, Blankenhorn E, Tung K, Teuscher C. The postnatal maternal environment affects autoimmune disease susceptibility in A/J mice. Cellular immunology. 2009;260(2): 119-27. PMID: 19914609 | PMCID: PMC2795069
  • Guth A, Detanico T, Smith D, Tung K, Bonorino C, Wysocki L. Spontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3. Lupus. 2009;18(4): 299-308. PMID: 19276297 | PMCID: PMC2892212
  • Wheeler K, Samy E, Tung K. Cutting edge: normal regional lymph node enrichment of antigen-specific regulatory T cells with autoimmune disease-suppressive capacity. Journal of immunology (Baltimore, Md. : 1950). 2009;183(12): 7635-8. PMID: 19923458 | PMCID: PMC2872190
  • Chavali A, Gianchandani E, Tung K, Lawrence M, Peirce S, Papin J. Characterizing emergent properties of immunological systems with multi-cellular rule-based computational modeling. Trends in immunology. 2008;29(12): 589-99. PMID: 18964301
  • Samy E, Wheeler K, Roper R, Teuscher C, Tung K. Cutting edge: Autoimmune disease in day 3 thymectomized mice is actively controlled by endogenous disease-specific regulatory T cells. Journal of immunology (Baltimore, Md. : 1950). 2008;180(7): 4366-70. PMID: 18354156
  • Samy E, Setiady Y, Ohno K, Pramoonjago P, Sharp C, Tung K. The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function. Immunological reviews. 2006;212 170-84. PMID: 16903914
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