Judith A. Woodfolk

Education

  • PhD, University of Virginia
  • MD, Sheffield University
  • MBChB, Sheffield University
  • MB,ChB, Sheffield University

Contact

Research Interest(s)

Immune Response to Allergens

Research Description

Studies in my lab focus on defining T cell responses to allergens using human-based in vitro systems. Ongoing projects include: Mechanisms of T Cell Dysregulation in Severe Allergic Disease; Investigation of the Immunomodulatory Properties of Novel Allergen Molecules Which Target Antigen Presenting Cells; Analysis of the Mechanism of Action of the Th2-Promoting Cytokine, TSLP, in Allergic Individuals.

Selected Publications

  • Allakhverdi Z, Comeau M, Armant M, Agrawal R, Woodfolk J, Sehmi R, Howie K, Gauvreau G, Delespesse G. Mast Cell-Activated Bone Marrow Mesenchymal Stromal Cells Regulate Proliferation and Lineage Commitment of CD34(+) Progenitor Cells. Frontiers in immunology. 2014;4 461. PMID: 24381572 | PMCID: PMC3865761
  • Romeo M, Agrawal R, Pomés A, Woodfolk J. A molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease. The Journal of allergy and clinical immunology. 2013;133(4): 952-60. PMID: 24084078 | PMCID: PMC3969406
  • Commins S, Kelly L, Rönmark E, James H, Pochan S, Peters E, Lundbäck B, Nganga L, Cooper P, Hoskins J, Eapen S, Matos L, McBride D, Heymann P, Woodfolk J, Perzanowski M, Platts-Mills T. Galactose-α-1,3-galactose-specific IgE is associated with anaphylaxis but not asthma. American journal of respiratory and critical care medicine. 2012;185(7): 723-30. PMID: 22281828 | PMCID: PMC3326422
  • Agrawal R, Wisniewski J, Woodfolk J. The role of regulatory T cells in atopic dermatitis. Current problems in dermatology. 2011;41 112-24. PMID: 21576952
  • Erwin E, Woodfolk J, Ronmark E, Perzanowski M, Platts-Mills T. The long-term protective effects of domestic animals in the home. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2011;41(7): 920-2. PMID: 21668815
  • Platts-Mills T, Woodfolk J. Allergens and their role in the allergic immune response. Immunological reviews. 2011;242(1): 51-68. PMID: 21682738
  • Hulse K, Reefer A, Engelhard V, Patrie J, Ziegler S, Chapman M, Woodfolk J. Targeting allergen to FcgammaRI reveals a novel T(H)2 regulatory pathway linked to thymic stromal lymphopoietin receptor. The Journal of allergy and clinical immunology. 2010;125(1): 247-56.e1-8. PMID: 20109752 | PMCID: PMC2814452
  • Reefer A, Hulse K, Lannigan J, Solga M, Wright P, Kelly L, Patrie J, Chapman M, Woodfolk J. Flow cytometry imaging identifies rare T(H)2 cells expressing thymic stromal lymphopoietin receptor in a "proallergic" milieu. The Journal of allergy and clinical immunology. 2010;126(5): 1049-58, 1058.e1-10. PMID: 20888036 | PMCID: PMC3034251
  • Platts-Mills T, Erwin E, Heymann P, Woodfolk J. Pro: The evidence for a causal role of dust mites in asthma. American journal of respiratory and critical care medicine. 2009;180(2): 109-13; discussion 120-1. PMID: 19395504
  • Platts-Mills T, Woodfolk J. Trichophyton asthma. Chest. 2009;135(4): 887-8. PMID: 19349392