George T. Gillies

Primary Appointment

  • Research Professor, Mechanical and Aerospace Engineering

Contact

Research Interest(s)

Design of novel neurosurgical instrumentation systems, including magnetic stereotactic devices

Research Description

Our research centers on the development of magnetic stereotaxis and medical magnetic manipulation systems for use in neurosurgical, neuroradiological, and other clinical applications. Magnetic stereotaxis is a technique for using magnetic fields and gradients outside the patient’s head as a means of navigating an implanted device such as a drug delivery catheter or an intracerebrovascular probe for thrombosing aneurysms. An important part of this effort is the design and prototyping of novel neurosurgical instruments and technologies used in conjunction with magnetic stereotaxis or in related surgical procedures. Other research includes studies of spinal mechanics and the kinematics of the suboccipital region of the craniomandibular complex, the development of stem cell-based techniques for the treatment of Parkinson’s disease, and the development of antisense gene therapy strategies for neoplastic diseases of the central nervous system.

Selected Publications

  • Flouty O, Oya H, Kawasaki H, Wilson S, Reddy C, Jeffery N, Brennan T, Gibson-Corley K, Utz M, Gillies G, Howard M. A new device concept for directly modulating spinal cord pathways: initial in vivo experimental results. Physiological measurement. 2012;33(12): 2003-15. PMID: 23151433
  • Gibson-Corley K, Oya H, Flouty O, Fredericks D, Jeffery N, Gillies G, Howard M. Ovine tests of a novel spinal cord neuromodulator and dentate ligament fixation method. Journal of investigative surgery : the official journal of the Academy of Surgical Research. 2012;25(6): 366-74. PMID: 23215793
  • Oya H, Howard M, Shurig R, Gillies G. Spinal canal surrogate for testing intradural implants. Journal of medical engineering & technology. 2012;36(8): 407-10. PMID: 22953718
  • Song S, Gillies G, Begley M, Utz M, Broaddus W. Inductively coupled microfluidic pressure meter for in vivo monitoring of cerebrospinal fluid shunt function. Journal of medical engineering & technology. 2012;36(3): 156-62. PMID: 22316101
  • Song S, Gillies G, Howard M, Kuhnley B, Utz M. Power and signal transmission protocol for a contactless subdural spinal cord stimulation device. Biomedical microdevices. 2012;15(1): 27-36. PMID: 22892642
  • Thiele R, Colquhoun D, Gillies G, Tiouririne M. Manipulation of hyperbaric lidocaine using a weak magnetic field: a pilot study. Anesthesia and analgesia. 2012;114(6): 1365-7. PMID: 22451591
  • Wilson S, Howard M, Rossen J, Brennan T, Dalm B, Dahdaleh N, Utz M, Gillies G. Pulsatile spinal cord surrogate for intradural neuromodulation studies. Journal of medical engineering & technology. 2011;36(1): 22-5. PMID: 22188575