Eyleen Jorgelina O'Rourke

Primary Appointment

  • Assistant Professor, Biology

Contact

Research Interest(s)

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Research Description

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Selected Publications

  • Zhang H, Chang J, Guo B, Hansen M, Jia K, Kovács A, Kumsta C, Lapierre L, Legouis R, Lin L, Lu Q, Meléndez A, O'Rourke E, Sato K, Sato M, Wang X, Wu F. Guidelines for monitoring autophagy in Caenorhabditis elegans. Autophagy. 2015;11(1): 9-27. PMID: 25569839
  • Wählby C, Conery A, Bray M, Kamentsky L, Larkins-Ford J, Sokolnicki K, Veneskey M, Michaels K, Carpenter A, O'Rourke E. High- and low-throughput scoring of fat mass and body fat distribution in C. elegans. Methods (San Diego, Calif.). 2014;68(3): 492-9. PMID: 24784529 | PMCID: PMC4112171
  • O'Rourke E, Kuballa P, Xavier R, Ruvkun G. ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. Genes & development. 2013;27(4): 429-40. PMID: 23392608 | PMCID: PMC3589559
  • O'Rourke E, Ruvkun G. MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability. Nature cell biology. 2013;15(6): 668-76. PMID: 23604316 | PMCID: PMC3723461
  • Wählby C, Kamentsky L, Liu Z, Riklin-Raviv T, Conery A, O'Rourke E, Sokolnicki K, Visvikis O, Ljosa V, Irazoqui J, Golland P, Ruvkun G, Ausubel F, Carpenter A. An image analysis toolbox for high-throughput C. elegans assays. Nature methods. 2012;9(7): 714-6. PMID: 22522656 | PMCID: PMC3433711
  • O'Rourke E, Conery A, Moy T. Whole-animal high-throughput screens: the C. elegans model. Methods in molecular biology (Clifton, N.J.). 2009;486 57-75. PMID: 19347616
  • O'Rourke E, Soukas A, Carr C, Ruvkun G. C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell metabolism. 2009;10(5): 430-5. PMID: 19883620 | PMCID: PMC2921818
  • Wang M, O'Rourke E, Ruvkun G. Fat metabolism links germline stem cells and longevity in C. elegans. Science (New York, N.Y.). 2008;322(5903): 957-60. PMID: 18988854 | PMCID: PMC2760269
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