Christopher Stroupe


  • SB, Massachusetts Institute of Technology
  • PhD, Yale University

Primary Appointment

  • Assistant Professor, Molecular Physiology and Biological Physics


Research Interest(s)

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Selected Publications

  • Zick M, Stroupe C, Orr A, Douville D, Wickner W. Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion. eLife. 2014;3 e01879. PMID: 24596153 | PMCID: PMC3937803
  • The yeast vacuolar Rab GTPase Ypt7p has an activity beyond membrane recruitment of the homotypic fusion and protein sorting-Class C Vps complex. The Biochemical journal. 2012;443(1): 205-11. PMID: 22417749 | PMCID: PMC3855318
  • Autophagy: cells SNARE selves. Current biology : CB. 2011;21(18): R697-9. PMID: 21959158
  • Hickey C, Stroupe C, Wickner W. The major role of the Rab Ypt7p in vacuole fusion is supporting HOPS membrane association. The Journal of biological chemistry. 2009;284(24): 16118-25. PMID: 19386605 | PMCID: PMC2713515
  • Stroupe C, Hickey C, Mima J, Burfeind A, Wickner W. Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(42): 17626-33. PMID: 19826089 | PMCID: PMC2764952
  • Stroupe C, Collins K, Fratti R, Wickner W. Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p. The EMBO journal. 2006;25(8): 1579-89. PMID: 16601699 | PMCID: PMC1440844