Cedric L. Williams

Primary Appointment

  • Professor, Psychology

Contact

Research Interest(s)

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Research Description

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viagra for sale in usa stores Our research is designed to understand how hormonal changes in the body and the physiological changes they produce after exposure to meaningful or emotionally arousing events, influences neural circuits in the brain to encode these experiences into memory more effectively. These types of questions are approached with 1) the use of a battery of behavioral learning tasks with laboratory rodents, 2) in vivo microdialysis to identify which chemical neurotransmitters are released in the brain while they are learning and 3) immunohistochemistry to reveal the brain regions activated by these experiences. The combined approaches will reveal the functional relevance of anatomical and chemical interactions that take place in the brain during the memory formation process. An understanding of how meaningful or arousing events influence neural activity in specific anatomical regions will provide a model of how the brain transforms representations of everyday experiences into permanent memories. Contact: Prof. Williams clw3b@virginia.edu Website: www.virginia.edu/psychology/people/detail.php?id=174

Selected Publications

  • Young E, Williams C. Differential activation of amygdala Arc expression by positive and negatively valenced emotional learning conditions. Frontiers in behavioral neuroscience. 2013;7 191. PMID: 24367308 | PMCID: PMC3852216
  • Chen C, Williams C. Interactions between epinephrine, ascending vagal fibers, and central noradrenergic systems in modulating memory for emotionally arousing events. Frontiers in behavioral neuroscience. 2012;6 35. PMID: 22754515 | PMCID: PMC3384987
  • Park S, Williams C. Contribution of serotonin type 3 receptors in the successful extinction of cued or contextual fear conditioned responses: interactions with GABAergic signaling. Reviews in the neurosciences. 2012;23(5): 555-69. PMID: 23087085
  • McIntyre C, McGaugh J, Williams C. Interacting brain systems modulate memory consolidation. Neuroscience and biobehavioral reviews. 2011;36(7): 1750-62. PMID: 22085800 | PMCID: PMC3315607
  • Young E, Williams C. Valence dependent asymmetric release of norepinephrine in the basolateral amygdala. Behavioral neuroscience. 2010;124(5): 633-44. PMID: 20939663
  • King S, Williams C. Novelty-induced arousal enhances memory for cued classical fear conditioning: interactions between peripheral adrenergic and brainstem glutamatergic systems. Learning & memory (Cold Spring Harbor, N.Y.). 2009;16(10): 625-34. PMID: 19794188
  • Kerfoot E, Chattillion E, Williams C. Functional interactions between the nucleus tractus solitarius (NTS) and nucleus accumbens shell in modulating memory for arousing experiences. Neurobiology of learning and memory. 2007;89(1): 47-60. PMID: 17964820 | PMCID: PMC2175480