Brant Isakson

Education

  • PhD, University of Wyoming

Primary Appointment

  • Associate Professor, Molecular Physiology and Biological Physics

Contact

Research Interest(s)

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Research Description

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Selected Publications

  • Billaud M, Lohman A, Johnstone S, Biwer L, Mutchler S, Isakson B. Regulation of cellular communication by signaling microdomains in the blood vessel wall. Pharmacological reviews. 2014;66(2): 513-69. PMID: 24671377 | PMCID: PMC3973613
  • Cechova S, Zeng Q, Billaud M, Mutchler S, Rudy C, Straub A, Chi L, Chan F, Hu J, Griffiths R, Howell N, Madsen K, Jensen B, Palmer L, Carey R, Sung S, Malakauskas S, Isakson B, Le T. Loss of collectrin, an angiotensin-converting enzyme 2 homolog, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction. Circulation. 2013;128(16): 1770-80. PMID: 24048198
  • Lohman A, Billaud M, Isakson B. Mechanisms of ATP release and signalling in the blood vessel wall. Cardiovascular research. 2012;95(3): 269-80. PMID: 22678409 | PMCID: PMC3400358
  • Lohman A, Weaver J, Billaud M, Sandilos J, Griffiths R, Straub A, Penuela S, Leitinger N, Laird D, Bayliss D, Isakson B. S-nitrosylation inhibits pannexin 1 channel function. The Journal of biological chemistry. 2012;287(47): 39602-12. PMID: 23033481 | PMCID: PMC3501028
  • Straub A, Lohman A, Billaud M, Johnstone S, Dwyer S, Lee M, Bortz P, Best A, Columbus L, Gaston B, Isakson B. Endothelial cell expression of haemoglobin α regulates nitric oxide signalling. Nature. 2012;491(7424): 473-7. PMID: 23123858 | PMCID: PMC3531883
  • Billaud M, Lohman A, Straub A, Looft-Wilson R, Johnstone S, Araj C, Best A, Chekeni F, Ravichandran K, Penuela S, Laird D, Isakson B. Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction. Circulation research. 2011;109(1): 80-5. PMID: 21546608 | PMCID: PMC3135971
  • Chekeni F, Elliott M, Sandilos J, Walk S, Kinchen J, Lazarowski E, Armstrong A, Penuela S, Laird D, Salvesen G, Isakson B, Bayliss D, Ravichandran K. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature. 2010;467(7317): 863-7. PMID: 20944749 | PMCID: PMC3006164
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