Barry T. Hinton


  • BS, University of East London
  • PhD, The Babraham Institute

Primary Appointment

  • Professor, Cell Biology


Research Interest(s)

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Research Description

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Selected Publications

  • Xu B, Washington A, Hinton B. PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility. Proceedings of the National Academy of Sciences of the United States of America. 2014;111(52): 18643-8. PMID: 25512490 | PMCID: PMC4284526
  • Xu B, Yang L, Hinton B. The Role of fibroblast growth factor receptor substrate 2 (FRS2) in the regulation of two activity levels of the components of the extracellular signal-regulated kinase (ERK) pathway in the mouse epididymis. Biology of reproduction. 2013;89(2): 48. PMID: 23782834 | PMCID: PMC4076368
  • Hinton B, Galdamez M, Sutherland A, Bomgardner D, Xu B, Abdel-Fattah R, Yang L. How do you get six meters of epididymis inside a human scrotum? Journal of andrology. 2011;32(6): 558-64. PMID: 21441421
  • Mital P, Hinton B, Dufour J. The blood-testis and blood-epididymis barriers are more than just their tight junctions. Biology of reproduction. 2011;84(5): 851-8. PMID: 21209417
  • Xu B, Abdel-Fattah R, Yang L, Crenshaw S, Black M, Hinton B. Testicular lumicrine factors regulate ERK, STAT, and NFKB pathways in the initial segment of the rat epididymis to prevent apoptosis. Biology of reproduction. 2011;84(6): 1282-91. PMID: 21311037 | PMCID: PMC3099589
  • Hinton B, Cooper T. The epididymis as a target for male contraceptive development. Handbook of experimental pharmacology. 2010; 117-37. PMID: 20839090
  • Snyder E, Small C, Bomgardner D, Xu B, Evanoff R, Griswold M, Hinton B. Gene expression in the efferent ducts, epididymis, and vas deferens during embryonic development of the mouse. Developmental dynamics : an official publication of the American Association of Anatomists. 2010;239(9): 2479-91. PMID: 20652947 | PMCID: PMC2939230
  • Xu B, Yang L, Lye R, Hinton B. p-MAPK1/3 and DUSP6 regulate epididymal cell proliferation and survival in a region-specific manner in mice. Biology of reproduction. 2010;83(5): 807-17. PMID: 20650883 | PMCID: PMC2959110
  • Archambeault D, Tomaszewski J, Joseph A, Hinton B, Yao H. Epithelial-mesenchymal crosstalk in Wolffian duct and fetal testis cord development. Genesis (New York, N.Y. : 2000). 2008;47(1): 40-8. PMID: 18979542 | PMCID: PMC2877590
  • Cotton L, O'Bryan M, Hinton B. Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction. Endocrine reviews. 2008;29(2): 193-216. PMID: 18216218 | PMCID: PMC2528845
  • Joseph A, Yao H, Hinton B. Development and morphogenesis of the Wolffian/epididymal duct, more twists and turns. Developmental biology. 2008;325(1): 6-14. PMID: 18992735 | PMCID: PMC2639655
  • Miecz D, Januszewicz E, Czeredys M, Hinton B, Berezowski V, Cecchelli R, NaƂecz K. Localization of organic cation/carnitine transporter (OCTN2) in cells forming the blood-brain barrier. Journal of neurochemistry. 2007;104(1): 113-23. PMID: 17995936
  • Fox S, Yang L, Hinton B. Identifying putative contraceptive targets by dissecting signal transduction networks in the epididymis using an in vivo electroporation (electrotransfer) approach. Molecular and cellular endocrinology. 2006;250(1): 196-200. PMID: 16423449
  • Yang L, Fox S, Kirby J, Troan B, Hinton B. Putative regulation of expression of members of the Ets variant 4 transcription factor family and their downstream targets in the rat epididymis. Biology of reproduction. 2006;74(4): 714-20. PMID: 16394217
  • Kirby J, Yang L, Labus J, Lye R, Hsia N, Day R, Cornwall G, Hinton B. Characterization of epididymal epithelial cell-specific gene promoters by in vivo electroporation. Biology of reproduction. 2004;71(2): 613-9. PMID: 15115732
  • Lye R, Hinton B. Technologies for the study of epididymal-specific genes. Molecular and cellular endocrinology. 2004;216(1): 23-30. PMID: 15109741