The Cell Biology program provides outstanding training in research leading to the development of PhD trainees as independent investigators in a vibrant and rapidly evolving field.  Through a comprehensive training experience that emphasizes original research, interdisciplinary courses, and advanced topical colloquia, trainees have the opportunity to explore fundamental questions in many areas including molecular mechanisms of cell function; regulation of growth, differentiation and reproduction; cell interactions in migration; embryonic patterning in development; and morphogenesis of cells, tissues and organs.

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Program Faculty

  • Paul N. Adler
    Planar signaling, polarity and morphogenesis.
  • Huiwang Ai
    Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
  • Robert A. Bloodgood
    Cell-Surface Glycoprotein Dynamics and Cell Locomotion
  • George S. Bloom
    Pathogenic mechanisms in Alzheimer’s Disease and other neurodegenerative disorders
  • James E. Casanova
    Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
    Cell Biology of bacterial pathogenesis.
    The innate immune response to bacterial infection.
  • J. David Castle
    Intracellular cholesterol and the regulation of insulin secretion and membrane trafficking.
  • Jeffrey T. Corwin
    Regeneration and Developmental Biology of the Hearing and Balance Organs in the Vertebrate Ear.
  • Douglas W. DeSimone
    Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis
  • Noelle Dwyer
    Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance
  • Adrian J. Halme
    Regeneration and Systemic Responses to Tissue Damage
  • Barry T. Hinton
    Morphogenesis of the Developing Wolffian/Epididymal duct
  • David F Kashatus
    The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
  • Raymond E. Keller
    Cellular and molecular mechanisms of morphogenesis
  • Keith G. Kozminski
    Regulation of Polarized Morphogenesis
  • Sarah C Kucenas
    The role of glia in the development, maintenance and regeneration of the nervous system
  • Gordon W. Laurie
    Role of Prosecretory Mitogen ‘Lacritin’ in Epithelial Homeostasis, Secretion and Innate Defense
  • Xiaowei Lu
    Developmental regulation of planar cell polarity in the mammalian nervous system
  • Eyleen Jorgelina O’Rourke
    Obesity and Aging
  • David Parichy
    Long-distance communication by specialized cellular projections, intersections of hormonal controls with local mechanisms of differentiation and morphogenesis, establishment and recruitment of post-embryonic stem cells during development and regeneration,
  • Kwon-Sik Park
    Mechanisms of tumor progression and homeostasis
  • K. Kevin Pfister
    Regulation of Cytoplasmic Dynein for Membrane Bounded Organelle Trafficking in Axons
  • Kodi S. Ravichandran
    Apoptotic cell clearance mechanisms in health and disease
  • Stefanie Redemann
    Spindle assembly, the structure function relation and the basics of the huge variability of spindle size, architecture and mechanics between different tissues as well as different species
  • Dorothy A. Schafer
    Mechanisms of actin assembly during cell migration and membrane traffic
  • Jung-Bum Shin
    Auditory Neurobiology
  • Sarah Siegrist
    Regulation of neural stem cell proliferation by extracellular factors, local and systemic. Intrinsic signaling programs regulating neural stem cell fate decisions: death versus survival. Functional and molecular similarities between Drosophila and mammal
  • P. Todd Stukenberg
    Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
  • Ann E. Sutherland
    Cell Matrix Interactions In Mouse Development
  • Lukas K. Tamm
    Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
  • Bernard V. Thisse
    Molecular control of embryonic development
  • Christine I. Thisse
    Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine
  • Judith M. White
    Virus Entry into Cells: Mechanisms and Development of Anti-Viral Therapeutics
  • Bettina Winckler
    Endosomal function and dysfunction in neurons
  • David Wotton
    Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling
  • Jing Yu
    Mammalian kidney development
  • Scott O. Zeitlin
    Mechanisms of Huntington’s Disease Pathogenesis
  • Hui Zong
    Mouse models of brain cancers