The Biophysics Program is an interdisciplinary degree-granting program that has faculty in 13 departments over three schools or colleges across the Grounds of the University of Virginia. The faculty and their trainees conduct research in a wide range of areas relevant to basic biological phenomena as well as human health, while sharing common ground in the use of quantitative approaches that emphasize chemistry, computation, mathematics and physics.
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- Huiwang Ai
Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
- Stefan Bekiranov
Physical Modeling of Microarray Hybridization; Analysis of Genomic Tiling Array Data; Bioinformatics; Computational Biology; Regulatory Networks
- John H. Bushweller
Structural and Functional Basis for Oncogenesis; Targeted Drug Development; Structural Studies of Membrane Proteins
- David S. Cafiso
Molecular Mechanisms for Membrane Transport and Cell Signaling
- J. David Castle
Intracellular cholesterol and the regulation of insulin secretion and membrane trafficking.
- Linda Columbus
Biophysical Chemistry: Membrane protein structure, function, and dynamics
- Zygmunt S. Derewenda
Structure-function relationships in proteins
- Kateri H. DuBay
The design of self-assembling nanomaterials
- Edward H. Egelman
Structure and Function of Macromolecular Complexes Using Electron Microscopy
- Roseanne M. Ford
Bacterial attachment and biofilms, microbial transport in porous media
- Andreas Gahlmann
Bacterial cell biology at the molecular level
- Jennifer Guler
Cell Biology and Parasitology.
- Jeffrey W. Holmes
Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.
- Ku-Lung Hsu
Lipid Metabolism in Inflammation and Immunity
- Donald F. Hunt
- Brant Isakson
Intercellular communication as it relates to blood pressure regulation
- Peter M. Kasson
Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.
- Kimberly Kelly
Advancement in the design of imaging agents; molecular imaging and radiological sciences.
- Bijoy Kundu
Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy
- James P. Landers
Bioanalytical Chemistry on Microchips
- Michael B. Lawrence
Vascular and Molecular Engineering
- Wladek Minor
Structure-Function Relationships in Proteins; Structural Genomics; Bioinformatics
- Cameron Mura
Structure, function & evolution of RNA-processing assemblies; structural and computational biology; molecular biophysics
- Robert K. Nakamoto
Structure-Function of Active Transporters
- Jason Papin
Systems biology, infectious disease, cancer, toxicology, metabolic engineering
- William R. Pearson
Protein Evolution; Computational Biology
- Shayn M. Peirce-Cottler
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
- Rebecca Pompano
Our lab develops methods based on microfluidic culture systems, bioanalytical techniques, and spatially resolved simulations to quantify the spatiotemporal dynamics of the inflammatory cascade and develop targeted therapies.
- Owen Pornillos
Structure and assembly of HIV Virus/host interactions Structural biology of the innate immune system
- Jeffrey J. Saucerman
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
- Avril V. Somlyo
Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.
- Swapnil Sonkusare
Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension
- P. Todd Stukenberg
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
- Nathan Swami
Molecular and bioelectric devices; tissue regeneration.
- Lukas K. Tamm
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
- B. Jill Venton
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
- Judith M. White
Virus Entry into Cells: Mechanisms and Development of Anti-Viral Therapeutics
- Michael C. Wiener
Structural biology (esp. crystallography) of integral membrane proteins; TonB-dependent active transport across the bacterial outer membrane; cancer-related membrane proteins; crystallization methods development
- Mark Yeager
Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus
- Jochen Zimmer
Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.